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Visar resultat 1 - 5 av 6 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Theoretical description of Ti and Ti alloys from first principles

    Författare :Natalia Skripnyak; Igor Abrikosov; Iryna Yakimenko; Sergey Simak; Zi-Kui Liu; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; T; Ti alloys; DFT; molecular dynamics; thermodynamic properties; elastic properties;

    Sammanfattning : Modern world is known for many advanced technologies and solutions to complex problems. Technical progress runs at high speed. In order to most effectively use materials, given to us by Nature, it is important to know their properties. To do laboratory experiments is often too expensive and time consuming. LÄS MER

  3. 2. Signaling pathways in the development of female germ cells

    Författare :Deepak Adhikari; Kui Liu; Elisabet Stener-Victorin; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ovary; primordial follicle; activation; mTORC₁; PI₃K; oocyte maturation; MPF; Cdk₁; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : Primordial follicles are the first small follicles to appear in the mammalian ovary. Women are born with a fixed number of primordial follicles in the ovaries. Once formed, the pool of primordial follicles serves as a source of developing follicles and oocytes. LÄS MER

  4. 3. Molecular studies of intra-oocyte phosphatidylinositol 3 kinase (PI3K) signaling pathway in controlling female fertility

    Författare :Pradeep Reddy Dubbaka Venu; Kui Liu; Evelyn Telfer; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Primordial follicles; Oocyte; PI3K; Biochemistry; Biokemi; Developmental Biology; miljömedicinsk utvecklingsbiologi;

    Sammanfattning : The primordial follicle pool is the main source of developing follicles in the ovary. The length of reproductive life and the onset of menopause are governed by the amount of primordial follicles in the ovary. LÄS MER

  5. 4. The functional roles of the intra-oocyte phosphatidylinositol 3-kinase (PI3K) signaling in controlling follicular development in mice

    Författare :Krishna Rao Jagarlamudi; Kui Liu; Lena Sahlin; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oocyte; PI3K signaling; primordial follicle; Obstetrics and gynaecology; Obstetrik och gynekologi; Developmental Biology; miljömedicinsk utvecklingsbiologi;

    Sammanfattning : The key functions of the mammalian ovary are the production of fertilizable oocytes and thesecretion of steroid hormones. At the time of birth the human ovary is composed of basic unitstermed primordial follicles. Primordial follicles are long-lived structures in the ovary and some ofthem last until the woman reaches menopause. LÄS MER

  7. 5. Studies of phosphatidylinositol 3 kinase (PI3K) signaling pathway in mammalian ovarian follicle activation and development

    Författare :Singareddy Rajareddy; Kui Liu; Anneli Stavreus-Evers; Umeå universitet; []
    Nyckelord :oocyte; follicular development; P13K pathway; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : The intra-oocyte signaling pathways that control oocyte growth and early follicular development are largely unknown. The aim of this thesis was to investigate the regulation and functions of phosphatidylinositol 3 kinase (PI3K) pathway in the oocyte, focusing in the roles of Foxo3a, p27, and Pten (phosphatase and tensin homolog deleted on chromosome ten). LÄS MER