Sökning: "Jakob Regberg"

Hittade 2 avhandlingar innehållade orden Jakob Regberg.

1. 1. Cell-penetrating peptide based nanocomplexes for oligonucleotide delivery

   Författare :Jakob Regberg; Ülo Langel; Arwyn Tomos Jones; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cell-penetrating peptides; oligonucleotides; gene therapy; drug delivery; scavenger receptors; blood-brain barrier; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Sammanfattning : Oligonucleotide-based drugs hold great promise for the treatment of many types of diseases, ranging from genetic disorders to viral infections and cancer. The problem is that efficient delivery across the cell membrane is required for oligonucleotides to have their desired effect. Cell-penetrating peptides (CPPs) provide a solution to this problem. LÄS MER

3. 2. Rational design and applications of cell-penetrating peptides

   Författare :Jakob Regberg; Ülo Langel; Amelie Eriksson Karlström; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Sammanfattning : Cell-penetrating peptides are peptides capable of translocating the cellular membrane and entering the cell, either alone or together with a cargo. Potential applications of cell-penetrating peptides include drug delivery and gene therapy. LÄS MER