Sökning: "Immunoglobulin A"
Visar resultat 1 - 5 av 340 avhandlingar innehållade orden Immunoglobulin A.
1. Staphylococcal surface display in directed evolution
Sammanfattning : Engineered affinity proteins have together with naturally derived antibodies becomeindispensable tools in many areas of life-science and with the increasing number ofapplications, the need for high-throughput methods for generation of such different affinityproteins is evident. Today, combinatorial protein engineering is the most successful strategy toisolate novel non-immunoglobulin affinity proteins. LÄS MER
2. Studies on human plasma proteins with special reference to immunoglobulin light chains and a vitamin A transport protein complex
Sammanfattning : .... LÄS MER
3. Immunoglobulin A nephropathy and disease complications : register-based studies
Sammanfattning : Immunoglobulin A nephropathy (IgAN) is the commonest primary glomerular disease worldwide. A kidney biopsy is required for the diagnosis. IgA immune-complex depositions sets off a cascade leading to renal scarring, proteinuria and hypertension. LÄS MER
4. The ontogeny and regulation of human natural killer cells
Sammanfattning : Natural Killer (NK) cells are members of the innate lymphoid cell (ILC) family and take part in the detection and eradication of virus-infected and transformed cells. In this thesis, together with my colleagues I have investigated how NK cells and other ILCs develop and function during human fetal development, how NK cells are functionally regulated (educated) via the activating receptor KIR2DS1, and how NK cells in our body are affected during the early phase of an acute viral infection. LÄS MER
5. Regulation of immunoglobulin transcription
Sammanfattning : Each Ig V-region has its own upstream promoter and the promoter of a mature Ig gene is thereby selected during the V(D)J recombination process. Upon comparison, it is evident that only one transcription factor binding site, the octamer, is preserved within all promoters. LÄS MER