Sökning: "IGF binding proteins IGFBP"

Visar resultat 16 - 20 av 28 avhandlingar innehållade orden IGF binding proteins IGFBP.

1. 16. Growth factors and vasoactive substances in intrauterine growth restriction and preeclampsia

   Författare :Eva Östlund; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Cordocentesis; IUGR; preeclampsia; prediction; IGF-I; IGFBP- 1; TGF-beta 1; blood gases; hypoxia; vasoconstriction; endothelin; erythropoietin; fibronectin; placenta.;

   Sammanfattning : Fetal growth restriction (FGR) is, next to prematurity, the second leading cause of perinatal morbidity and mortality. To reduce perinatal morbidity and mortality it is important to identify such fetuses in utero in order to monitor their development, and to determine the most optimal time for delivery. LÄS MER

3. 17. Diabetic osteopathy : a study in the rat

   Författare :Tashfeen Ahmad; Karolinska Institutet; Karolinska Institutet; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Diabetes mellitus type 2; Goto-Kakizaki rat; bone mineral density; insulin-like growth factor-I; insulin-like growth factor binding protein 1; insulin-like growth factor binding protein 4; peripheral neuropathy; substance P; calcitonin gene-related peptide; neuropeptide Y; Diabetes mellitus type 2;

   Sammanfattning : The present study on non-obese Goto-Kakizaki (GK) rats with type-2 diabetes and neuropathy was an attempt to describe and define pertinent features of diabetic osteopathy. Altogether, the study included 33 GK rats aged 12 and 20 months, and 36 age-matched Wistar rats as controls. LÄS MER

4. 18. Insulin-like growth factor-I in the domestic cat : studies in health and disease

   Författare :Emma Strage; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
   Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

   Sammanfattning : Insulin-like growth factor-I (IGF-I) has growth promoting effects as well as insulin-like actions on metabolism. IGF-I associates with a family of six high affinity IGF-binding proteins (IGFBPs) and these interfere in immunoassays for IGF-I. LÄS MER

5. 19. Regulation of insulin-like growth factor-II in human liver

   Författare :Henrik von Horn; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :IG17-II; IGF2; IGFBPs; liver; hepatoblastoma; GH; hypoxia;

   Sammanfattning : Insulin-like growth factors-I and -II (IGF-I and -II) are mitogens in a number of cell types and also have insulin-like actions. IGF-II has an autocrine role in a variety of malignancies; and hypoglycemia is well documented in conditions associated with elevated IGF-II precursor forms in the circulation. LÄS MER

7. 20. Identification and evaluation of growth hormone antagonists

   Författare :Linda Rosengren; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : States in which Growth hormone (GH) levels are elevated have been implicated in several physiological disorders such as acromegaly, diabetic complications and progression of malignancies. Classical treatments for acromegaly are surgery and radiotherapy but also pharmacological therapies exist. LÄS MER