Sökning: "High-grade serous ovarian carcinoma"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden High-grade serous ovarian carcinoma.

  1. 1. Ovarian Carcinoma - Early Detection and Prognostication

    Författare :Laura Martin de la Fuente; Bröst- och ovarialcancer; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; High-grade serous ovarian carcinoma; early detection markers; pre-diagnostic cervical sample; copy number alterations CNA ; copy number signatures; Claudin-4; immune cell infiltration; PD-1 PD-L1 pathway;

    Sammanfattning : .... LÄS MER

  3. 2. Novel biomarkers associated with histotype and clinical outcome in early-stage ovarian carcinoma

    Författare :Hanna Engqvist; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ovarian carcinoma; histotype-specific diagnosis and prognosis; molecular biomarker; outcome prediction; integrative analysis;

    Sammanfattning : Ovarian cancer is a collective name for multiple malignancies deriving from or involving the ovary, mainly comprising five histotypes of epithelial origin (clear-cell (CCC), endometrioid (EC), high-grade serous (HGSC), low-grade serous (LGSC), and mucinous carcinomas (MC)) with varying clinical (e.g. LÄS MER

  4. 3. Molecular signatures of progression and chemoresistance in epithelial ovarian carcinoma

    Författare :My Björklund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Epithelial ovarian carcinoma (EOC) is a heterogeneous disease generally classified into five histopathological subtypes; low- and high-grade serous, endometrioid, clear cell and mucinous carcinomas. Although each subtype has distinct clinical and molecular characteristics, they are all treated with surgery and platinum/ taxane chemotherapy. LÄS MER

  5. 4. Immunohistochemical and molecular studies on ovarian cancer progression and prognosis

    Författare :Björn Nodin; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epithelial ovarian cancer; prognostic and predictive biomarkers; tissue microarrays; androgen receptor; RBM3; Chek1; Chek2; MCM3; Dachshund 2; SATB1; KRAS mutation;

    Sammanfattning : Epithelial ovarian cancer (EOC) is the most lethal malignancy of the female reproductive tract. Due to vague symptomatology, the majority of EOC patients are diagnosed in advanced clinical stages with poor survival rates, despite improvements in surgical techniques and the advent of targeted therapeutics. LÄS MER

  7. 5. Pelvic inflammatory disease and epithelial ovarian tumors

    Författare :Sarah Jonsson; Annika Idahl; Eva Lundin; Håkan Jonsson; Christer Borgfeldt; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Background: Epithelial ovarian cancer and borderline ovarian tumors consist of several histotypes in which high-grade serous carcinoma is the most common. The majority of epithelial ovarian tumors are considered to originate in the fimbriated end of the fallopian tubes. What initiates these tumors is far from completely understood. LÄS MER