Sökning: "HVRI"

Hittade 3 avhandlingar innehållade ordet HVRI.

  1. 1. Nucleic acid-based detection and characterization of hepatitis C virus

    Författare :Zhibing Yun; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HCV; PCR; genotype; HVRI; heterogeneity; IFN-a; immunodeficiency;

    Sammanfattning : Nucleic acid-based methods were developed to detect and characterize the HCV genome in immunocompetent and immunodeficient patents of whom some were IFN-a treated. HCV RNA was found in most sera (95%), livers (97%) and PBMC (100%) of patients with confirmed chronic hepatitis, but also in sera (21%) of patients with indeterminate confirmatory antibody test, especially those with c22 antigen reactivity. LÄS MER

  3. 2. Hepatitis C virus infection : molecular analysis of transmission and immunity

    Författare :Tobias Allander; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Hepatitis C virus; Nosocomial transmission; Hemodialysis; Leukemia Envelope glycoprotein gp70; Hypervariable region 1; Antibodies; Phage display; Combinatorial antibody libraries; Neutralization.;

    Sammanfattning : Hepatitis C virus (HCV) is an important cause for chronic liver disease worldwide. Infection by HCV may resolve spontaneously, but in the majority of cases a chronic infection is established, that may result in liver cirrhosis and hepatocellular cancer. LÄS MER

  4. 3. Archaeological Genetics - Approaching Human History through DNA Analysis

    Författare :Evangelia Daskalaki; Anders Götherström; Mattias Jakobsson; Walther Parson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ancient DNA; pyrosequencing; molecular genetics; aDNA; neolithization; evolutionary genetics; mtDNA; viking age; archaeological genetics; genetik; evolutionsgenetik; naturvetenskap; neolitisering; vikingatid; arkeologisk genetik; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Sammanfattning : There are a variety of archaeological questions, which are difficult to assess by traditional archaeological methods. Similarly, there are genetic and population genetic questions about human evolution and migration that are difficult to assess by studying modern day genetic variation. LÄS MER