Sökning: "Godfried M Roomans"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden Godfried M Roomans.

1. 1. Quantitative electron probe X-ray microanalysis of biological specimens

   Författare :Godfried M. Roomans; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : The application of quantitative methods in electron probe X-ray microanalysis of biological specimens expands the scope of this technique. Accurate quantitation in biological X-ray microanalysis is not easy and a number of difficulties is typical for biological specimens. LÄS MER

3. 2. Approaches to Pharmacological Treatment and Gene Therapy of Cystic Fibrosis

   Författare :Anca Dragomir; Godfried M. Roomans; Robert Dormer; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anatomy; airway epithelium; colchicine; cystic fibrosis; chloride transport; genotype; heparin; phenotype; transfection; X-ray microanalysis; Anatomi; Anatomy; Anatomi;

   Sammanfattning : Cystic fibrosis (CF) is the most common lethal genetic disease in the white population. It is due to mutations in the gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR), a protein that functions mainly as a cAMP-activated chloride channel. LÄS MER

4. 3. Cell responses in infected and cystic fibrosis respiratory epithelium

   Författare :Rashida Hussain; Godfried M . Roomans; Maria Björkqvist; Ferenc Karpati; Hans Kollberg; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; airway epithelial cells; cystic fibrosis; bacterial infection; CFTR; ENaC; chloride transport; intracellular calcium; P. aeruginosa internalization; Biomedicin; Biomedicine;

   Sammanfattning : Respiratory Epithelium. Örebro Studies in Medicine 99. Cystic fibrosis (CF) is caused by a mutation in a cAMP-activated chloride (Cl-) channel (CFTR). Mortality and morbidity in CF is mainly due to the deregulated responses of the airway epithelial cells. LÄS MER

5. 4. Studies of Tight Junctions and Airway Surface Liquid in Airway Epithelium with Relevance to Cystic Fibrosis

   Författare :Harriet Nilsson; Godfried M Roomans; Anca Dragomir; Marie Johannesson; Olafur Baldurson; Uppsala universitet; []
   Nyckelord :;

   Sammanfattning : Cystic fibrosis (CF) is a multi-organ autosomal recessive disease of fluid-transporting epithelia, due to a mutation in the gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. CFTR is a cAMP-regulated Cl-channel involved in various regulatory processes. LÄS MER

7. 5. Advances in Pharmacological Treatment of Cystic Fibrosis

   Författare :Igor Oliynyk; Godfried M. Roomans; Marie Johannesson; Hugo R. de Jonge; Örebro universitet; []
   Nyckelord :Cystic fibrosis; CFTR; chloride transport; N-acetylcysteine; NO-donors; duramycin; intracellular calcium; azithromycin; MEDICINE; MEDICIN; Medicin; Medicine;

   Sammanfattning : Cystic fibrosis (CF) is an inborn, hereditary disease, due to mutations in the gene for a cAMP-activated chloride (Cl-) channel, the cystic fibrosis transmembrane conductance regulator (CFTR). As a result of impaired ion and water transport,the airway mucus is abnormally viscous, which leads to bacterial colonization. LÄS MER