Sökning: "Marie Johannesson"

Hittade 5 avhandlingar innehållade orden Marie Johannesson.

1. 1. Aspects on puberty and fertility among females with cystic fibrosis a multidisciplinary study on humans and rats

   Författare :Marie Johannesson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :cystic fibrosis; puberty; fertility; hormonal profiles; CFTR mRNA; MDR mRNA; rat brain; pregnant rat lung; psychosocial aspects.;

   Sammanfattning : Due to intensified symptomatic treatment, a majority of patients with cystic fibrosis (CF) now go through puberty and reach adulthood. This provides new challenges for the CF health care providers. LÄS MER

3. 2. Studies of Tight Junctions and Airway Surface Liquid in Airway Epithelium with Relevance to Cystic Fibrosis

   Författare :Harriet Nilsson; Godfried M Roomans; Anca Dragomir; Marie Johannesson; Olafur Baldurson; Uppsala universitet; []
   Nyckelord :;

   Sammanfattning : Cystic fibrosis (CF) is a multi-organ autosomal recessive disease of fluid-transporting epithelia, due to a mutation in the gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. CFTR is a cAMP-regulated Cl-channel involved in various regulatory processes. LÄS MER

4. 3. Advances in Pharmacological Treatment of Cystic Fibrosis

   Författare :Igor Oliynyk; Godfried M. Roomans; Marie Johannesson; Hugo R. de Jonge; Örebro universitet; []
   Nyckelord :Cystic fibrosis; CFTR; chloride transport; N-acetylcysteine; NO-donors; duramycin; intracellular calcium; azithromycin; MEDICINE; MEDICIN; Medicin; Medicine;

   Sammanfattning : Cystic fibrosis (CF) is an inborn, hereditary disease, due to mutations in the gene for a cAMP-activated chloride (Cl-) channel, the cystic fibrosis transmembrane conductance regulator (CFTR). As a result of impaired ion and water transport,the airway mucus is abnormally viscous, which leads to bacterial colonization. LÄS MER

5. 4. Ultrastructural Studies of the Airway Epithelium in Airway Diseases

   Författare :Eyman Shebani; Godfried M. Roomans; Marie Johannesson; Anil Mehta; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Morphology; asthma; cilia; corticosteroids; cytokines; desmosomes; Gaucher’s disease; montelukast; primary ciliary dyskinesia; transmission electron microscopy; Morfologi; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi;

   Sammanfattning : Ultrastructural studies of airway epithelium in airway disease are important for diagnosis and understanding the underlying pathology which helps clinicians to improve the patients' treatment.Airway biopsies from a 5-month old boy with respiratory problems and gastro-oesophageal reflux were studied by transmission electron microscopy (TEM). LÄS MER

7. 5. Chloride transport and inflammation in cystic fibrosis airways

   Författare :Georgia Varelogianni; Godfried Roomans; Marie Johannesson; Ólafur Baldersson; Örebro universitet; []
   Nyckelord :Cystic fibrosis; CFTR; chloride efflux; N-acetylcysteine; ambroxol; duramycin; Nod-like receptors; cytokines; Medicin; Medicine;

   Sammanfattning : Cystic fibrosis (CF) is one of the most common lethal, autosomal recessive inherited diseases among Caucasians. It is caused by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR), a chloride channel activated by cyclic AMP. LÄS MER