Sökning: "E-cadherin"

Visar resultat 41 - 45 av 59 avhandlingar innehållade ordet E-cadherin.

  1. 41. Role of syndecan-1 in tumor cell proliferation and epithelial-mesenchymal plasticity

    Författare :Ashish Kumar Singh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Syndecan-1 (SDC1) is a heparan sulfate proteoglycan (HSPG) intercalated in the cell membrane but also translocated to the cell nucleus in a regulated manner. SDC1 is involved in several malignancy-associated processes such as proliferation and migration. LÄS MER

  3. 42. MicroRNA-Mediated Migration of Colon Cancer Cells

    Författare :Anwar Algaber; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MicroRNA; Colon cancer; metastasis; HuR; RhoA; FHL2;

    Sammanfattning : Colorectal cancer (CRC) is the second most common cancer in women and third most common cancer in men worldwide. The cause of the majority of death related to CRC is believed to be the migration of cancer cells to distant organs which is known as cancer metastasis. LÄS MER

  4. 43. Invasive and Metastatic Properties of Advanced Prostate Cancer

    Författare :Karin Jennbacken; Göteborgs universitet; []
    Nyckelord :Prostate cancer; Androgen-independent; Castration-resistant; Metastasis; Invasion; Lymphangiogenesis; Cell adhesion; N-cadherin; VEGF-C; MRI;

    Sammanfattning : Prostate cancer is initially androgen-dependent (AD) and therefore androgen deprivation therapy (ADT) is generally used to treat advanced prostate cancer. However, the long-term treatment effects are insufficient and over time an androgen-independent (AI) tumor relapses, which is generally highly aggressive and metastatic. LÄS MER

  5. 44. Role of membrane associated molecules in liver fibrosis

    Författare :Peter Rosenberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Adhesion molecules; liver fibrosis; cholestasis; R-cadherin; N-CAM; EBP50; CFTR; cystic fibrosis; methotrexate; diabetes; over-weight; alcohol;

    Sammanfattning : The aim of the study was to evaluate the role of membrane associated proteins in tissue formation and remodeling, in normal embryogenesis and in liver disease. Molecules associated with cellular membranes provide a fundamental basis for cellular interactions during development, homeostasis and disease. LÄS MER

  7. 45. Search for markers and molecular mechanisms of aggressive endometrial cancer : profiling of aggressive vs non-aggressive endometrial cancers

    Författare :Sanaz Attarha; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Endometrial cancer is the seventh frequent type of cancer among women. Identification of new prognostic markers is important to optimize treatment and follow-up of all EC patients. Understanding the molecular mechanisms of carcinogenesis may pave through discovery of further EC molecular markers. LÄS MER