Sökning: "R-cadherin"

Hittade 4 avhandlingar innehållade ordet R-cadherin.

  1. 1. Role of membrane associated molecules in liver fibrosis

    Författare :Peter Rosenberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Adhesion molecules; liver fibrosis; cholestasis; R-cadherin; N-CAM; EBP50; CFTR; cystic fibrosis; methotrexate; diabetes; over-weight; alcohol;

    Sammanfattning : The aim of the study was to evaluate the role of membrane associated proteins in tissue formation and remodeling, in normal embryogenesis and in liver disease. Molecules associated with cellular membranes provide a fundamental basis for cellular interactions during development, homeostasis and disease. LÄS MER

  3. 2. The role of cell adhesion molecules in tissue formation and organogenesis

    Författare :Farzad Esni; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; cell adhesion cadherins N-CAM pancreas development mouse organogenesis;

    Sammanfattning : Cell adhesion molecules (CAMs) are cell surface glycoproteins that promote connection between two adjacent cells or between a cell and extra cellular matrix. These interactions are essential for tissue organisation during development and for the maintenance of tissue integrity in adult organisms. LÄS MER

  4. 3. Molecular regulation of thyroid development. New mechanisms of normal and defective morphogenesis

    Författare :Henrik Fagman; Göteborgs universitet; []
    Nyckelord :thyroid; congenital hypothyroidism; thyroid dysgenesis; cadherins; pharyngeal arch arteries; Shh; Tbx1;

    Sammanfattning : Congenital hypothyroidism (CH) is untreated a major cause of mental retardation. The majority of cases are due to malformations of the gland (dysgenesis). Little is known of molecular mechanisms regulating thyroid morphogenesis. LÄS MER

  5. 4. Classical cadherins and the thyroid. Studies on organ development and epithelial differentiation

    Författare :Mats Grände; Göteborgs universitet; []
    Nyckelord :Thyroid; cadherin; TGF-; EGF; MEK; development; EMT;

    Sammanfattning : The cadherins are key regulators of tissue patterning and organ formation. E-cadherin is important for cell-cell adhesion and promotes epithelial morphogenesis and maintenance of the epithelial phenotype. LÄS MER