Sökning: "Design of Experiments DoE"
Visar resultat 1 - 5 av 23 avhandlingar innehållade orden Design of Experiments DoE.
1. Contributions to the Use of Statistical Methods for Improving Continuous Production
Sammanfattning : Complexity of production processes, high computing capabilities, and massive datasets characterize today’s manufacturing environments, such as those of continuous andbatch production industries. Continuous production has spread gradually acrossdifferent industries, covering a significant part of today’s production. LÄS MER
2. Multivariate design of molecular docking experiments : An investigation of protein-ligand interactions
Sammanfattning : To be able to make informed descicions regarding the research of new drug molecules (ligands), it is crucial to have access to information regarding the chemical interaction between the drug and its biological target (protein). Computer-based methods have a given role in drug research today and, by using methods such as molecular docking, it is possible to investigate the way in which ligands and proteins interact. LÄS MER
3. Contributions to the use of designed experiments in continuous processes : a study of blast furnace experiments
Sammanfattning : Design of Experiments (DoE) contains techniques, such as factorial designs, that help experimenters maximize the information output from conducted experiments and minimize the amount of experimental work required to reach statistically significant results. The use of DoE in industrial processes is frequently and thoroughly described in literature. LÄS MER
4. Experimental Designs at the Crossroads of Drug Discovery
Sammanfattning : New techniques and approaches for organic synthesis, purification and biological testing are enabling pharmaceutical industries to produce and test increasing numbers of compounds every year. Surprisingly, this has not led to more new drugs reaching the market, prompting two questions – why is there not a better correlation between their efforts and output, and can it be improved? One possible way to make the drug discovery process more efficient is to ensure, at an early stage, that the tested compounds are diverse, representative and of high quality. LÄS MER
5. On design of experiments in continuous processes
Sammanfattning : Design of Experiments (DoE) includes powerful methods, such as factorial designs, to help maximize the information output from conducted experiments while minimizing the experimental work required for statistically significant results. The benefits of using DoE in industry are thoroughly described in the literature although the actual use of the methods in industry is far from being pervasive. LÄS MER