Sökning: "Cellular immunity"

Visar resultat 31 - 35 av 182 avhandlingar innehållade orden Cellular immunity.

  1. 31. Cellular immune responses to low density lipoprotein in atherosclerosis

    Författare :Andreas Hermansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Atherosclerosis is an inflammatory disease of the medium and large sized arterial vessels. Low density lipoprotein (LDL) particles carrying cholesterol are trapped within the arterial intima and elicit both innate as well as adaptive immune responses. LÄS MER

  3. 32. Role of POU/Oct transcription factors in Drosophila immunity

    Författare :Widad Dantoft; Ylva Engström; Anne Uv; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Antimicrobial peptides; Drosophila; host-pathogen interaction; immune gene expression; immune signaling; NF-kB; microbiota; POU Oct transcription factors; protein degradation; stress response; transcriptional regulation; Molecular Biology; molekylärbiologi;

    Sammanfattning : In response to infection, Drosophila melanogaster relies on the ability to mount a robust and potent innate immune response, characterized by induction of cellular and humoral processes. While rapid immune induction is of utmost importance, it is equally important to restrict and repress immune gene expression, where and when it is not needed. LÄS MER

  4. 33. Innate immunity and cardiac structure in chronic kidney disease

    Författare :Carin Wallquist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The inflammatory state of chronic kidney disease (CKD) leads to increased susceptibility to infections and cardiovascular complications. In this thesis we aimed to investigate development of inflammatory properties at different stages of CKD and changes in innate immunity as well as cardiac structure. LÄS MER

  5. 34. Defining the importance of protein geranylgeranylation in innate immunity

    Författare :Murali K Akula; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CAAX proteins; GGTase-I; RAC1; statins;

    Sammanfattning : RHO family proteins and other intracellular proteins are prenylated with a 20-carbon lipid—a product of the cholesterol synthesis pathway—by protein geranylgeranyltransferase type I (GGTase-I). Prenylation is widely believed to target proteins to membranes where they encounter effector molecules that stimulate GTP-binding and activation. LÄS MER

  7. 35. Development of novel immunization approaches to generate immunity in the female genital tract with special reference to genital herpes

    Författare :Sara Tengvall; Göteborgs universitet; []
    Nyckelord :female genital tract immunity; genital herpes; mucosal adjuvant; TLR; MyD88; CpG ODN;

    Sammanfattning : Development of mucosal vaccines for inducing immunity in the female reproductive tract would have profound implications for the prevention of sexually transmitted diseases. Despite numerous efforts, no such vaccines are currently available for human use. LÄS MER