Sökning: "Caveolin-1"

Visar resultat 11 - 15 av 21 avhandlingar innehållade ordet Caveolin-1.

  1. 11. A molecular approach to insulin signalling and caveolae in primary adipocytes

    Författare :Karin Stenkula; Fredrik Nyström; Peter Strålfors; Peter Arner; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; caveolae; insulin signalling; adipocytes; Medical cell biology; Medicinsk cellbiologi;

    Sammanfattning : The prevalence of type II diabetes is increasing at an alarming rate due to the western world lifestyle. Type II diabetes is characterized by an insulin resistance distinguished by impaired glucose uptake in adipose and muscle tissues. LÄS MER

  3. 12. Tissue Factor regulation, signaling and functions beyond coagulation with a focus on diabetes

    Författare :Desireé Edén; Agneta Siegbahn; Sofia Ramström; Uppsala universitet; []
    Nyckelord :Tissue factor; diabetes; cell signaling; coagulation; beta cells; adipocytes; apoptosis; lipolysis; micro RNA; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Background: Tissue factor (TF) is a 47 kDa transmembrane glycoprotein best known for initiating the coagulation cascade upon binding of its ligand FVIIa. Apart from its physiological role in coagulation, TF and TF/FVIIa signaling has proved to be involved in diseases such as diabetes, cancer and cardiovascular diseases. LÄS MER

  4. 13. Insulin signaling in primary adipocytes in insulin sensitive and insulin resistant states

    Författare :Siri Aili Fagerholm; Peter Strålfors; Mats Söderström; Ulf Smith; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Increasing numbers of people world-wide develops the disease type 2 diabetes. Development of type 2 diabetes is characterized by a shift from an insulin sensitive state to an insulin resistant state in peripheral insulin responding organs, which originates from the development of insulin resistance in the adipose tissue. LÄS MER

  5. 14. Biomarkers in nasopharyngeal carcinoma

    Författare :Zi-Ming Du; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Nasopharyngeal carcinoma (NPC) is one of the most common malignancies in certain areas of Southern China, Southeastern Asia and Northern Africa. Currently, evaluation of NPC prognosis is mainly based on the tumor-node-metastasis (TNM) staging system. LÄS MER

  7. 15. Transcriptional control mechanisms in the wall of the urinary bladder. Myocardin family coactivators and the transcriptomic impact of denervation

    Författare :Baoyi Zhu; Cellulär biomekanik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Urological problems can be caused by diseases that affect the bladder wall and its innervation. Contraction and relaxation of smooth muscle cells (SMCs) is essential for maintaining detrusor function and for emptying the bladder. LÄS MER