Sökning: "Cancer Progression"

Visar resultat 21 - 25 av 716 avhandlingar innehållade orden Cancer Progression.

1. 21. Role of ß-catenin and Leukotriene in Colon Cancer Progression

   Författare :Tavga Salim; Malmö Cellpatologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LTD4; β-catenin; E-cadherin; GSK-3β; inflammation; colorectal cancer;

   Sammanfattning : Abstract Colorectal cancer is the third most common cancer worldwide. Deregulation of Wnt/β-catenin signalling pathway is an early hallmark of colon cancer. Were nuclear accumulation of β-catenin is a marker of activated canonical Wnt/β-catenin signaling. One of the risk factors for development of colon cancer is inflammatory bowel disease. LÄS MER

3. 22. Identifying Essential Deubiquitinase Interactions and Targeting Protein Ubiquitination in Cancer

   Författare :Johannes Gubat; Padraig D´arcy; Stig Linder; Maria Turkina; Per Lindahl; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Deubiquitinase; b-AP15; Ubiquitin-proteasome system;

   Sammanfattning : Cancer is the second leading cause of death globally and is one of the most pressing health issues today. While significant advances have been made in cancer treatment, drug resistance and toxicity remain formidable obstacles to successful therapy. Thus, there is a need to find novel targets that pave the way for new cancer therapeutics. LÄS MER

4. 23. Prostate cancer and inflammatory genes

   Författare :Fredrik Lindmark; Henrik Grönberg; William G Nelson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; inflammation; association studies; epidemiology; MSR1; MIC-1; IL1-RN; Oncology; Onkologi; Oncology; onkologi;

   Sammanfattning : Prostate cancer remains a significant health concern for men throughout the world. Accumulating epidemiologic and molecular evidence suggests that inflammation is an important component in the aetiology of prostate cancer. LÄS MER

5. 24. Genetic epidemiology of prostate cancer

   Författare :Fredrik Wiklund; Henrik Grönberg; Douglas Easton; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; prostate cancer; epidemiology; genetics; linkage analysis; genome-wide scan; Onkologi; Oncology; Onkologi; Oncology; onkologi;

   Sammanfattning : Prostate cancer is a major health burden throughout the world, yet the etiology of prostate cancer is poorly understood. Evidence has accumulated supporting the existence of a hereditary form of this disease. LÄS MER

7. 25. Breast Cancer Prevention – lifestyle modifications or targeted interventions?

   Författare :Öykü Boraka; LUCC: Lunds universitets cancercentrum; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast cancer; breast cancer prevention; physical activity; mammography; breast density;

   Sammanfattning : Breast cancer is now the most frequently diagnosed cancer in the world. Breast cancer prevention has gained increasing attention due to increasing breast cancer incidence rates in the West and can be actualized through lifestyle modifications or targeted interventions. LÄS MER