Sökning: "Bioinformatik"

Visar resultat 21 - 25 av 439 avhandlingar innehållade ordet Bioinformatik.

  1. 21. Grid and High-Performance Computing for Applied Bioinformatics

    Författare :Jorge Andrade; Jacob Odeberg; Luciano Milanesi; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Grid computing; bioinformatics; genomics; proteomics; Bioinformatics; Bioinformatik;

    Sammanfattning : The beginning of the twenty-first century has been characterized by an explosion of biological information. The avalanche of data grows daily and arises as a consequence of advances in the fields of molecular biology and genomics and proteomics. LÄS MER

  2. 22. In silico analysis of microbial communities through constraint-based metabolic modelling

    Författare :Parizad Babaei; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; fermented food production; metagenomics; genome-scale metabolic model; community modelling; malnourishment; Microbial community; systems biology; lactic acid bacteria; gut microbiota; uniform randomised sampling;

    Sammanfattning : Microbial communities are involved in many vital biological processes from elemental cycles to sustaining human health. The bacterial assemblages are remarkably under-studied as they are reluctant to grow in the laboratory conditions. LÄS MER

  3. 23. Genetic factors affecting pregnancy duration in humans

    Författare :Jonas Bacelis; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; genomics; GWAS; Mendelian randomization; causal inference; preterm birth; pregnancy; gestation; height; text mining;

    Sammanfattning : This thesis investigates the mechanisms behind human pregnancy duration. Too short gestation is a direct cause of perinatal, neonatal, and infant mortality. Deviation from normal pregnancy length is also associated with a child's morbidity, even in the adulthood. LÄS MER

  4. 24. Sequence-based predictions of membrane-protein topology, homology and insertion

    Författare :Andreas Bernsel; Gunnar von Heijne; Volkhard Helms; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; membrane protein; topology prediction; hidden markov model; homology detection; Sec translocon; Bioinformatics; Bioinformatik; Biochemistry; biokemi;

    Sammanfattning : Membrane proteins comprise around 20-30% of a typical proteome and play crucial roles in a wide variety of biochemical pathways. Apart from their general biological significance, membrane proteins are of particular interest to the pharmaceutical industry, being targets for more than half of all available drugs. LÄS MER

  5. 25. Tumour evolution and novel biomarkers in breast cancer

    Författare :Jana Biermann; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; breast cancer; gene signature; molecular biomarkers; tumour clonality; genomic instability; Swedish haemangioma cohort;

    Sammanfattning : Several gene signatures have been proposed in the past two decades to improve outcome prediction for breast cancer patients and to guide treatment decisions. Current treatment guidelines, however, primarily focus on established clinicopathological features. LÄS MER