Sökning: "Barrett’s esophagus"
Visar resultat 1 - 5 av 12 avhandlingar innehållade orden Barrett’s esophagus.
1. The Columnar Lined Esophagus. Pathophysiological and Clinical Aspects
Sammanfattning : There is a persisting controversy concerning the definition, etiology and pathogenesis of Barrett's esophagus. The dramatic and parallel increase in the incidence of esophageal and junctional adenocarcinoma over the past decades justifies an evaluation of the pathophysiology of premalignant metaplastic changes of the esophagus and the gastroesophageal junction. LÄS MER
2. Aspects on endoscopic characterization and clinical management of Barrett's esophagus
Sammanfattning : Barrett's esophagus (BE) is considered to result from prolonged gastroesophageal reflux and is the only known precursor of esophageal adenocarcinoma. The clinical management of BE patients aims to control esophageal reflux to reduce mucosal injury and neoplastic progression, and to detect early neoplastic lesions in Barrett’s mucosa, suitable for curative endoscopic treatment. LÄS MER
3. p53 and neoplastic progression in Barrett's esophagus
Sammanfattning : Barrett's esophagus is a condition in which the normal squamous epithelium is replaced by columnar epithelium as a response to acid reflux. It develops as a complication in 10-20% of patients with gastroesophageal reflux disease. LÄS MER
4. Barrett's esophagus and the risk of adenocarcinoma
Sammanfattning : Barrett’s esophagus is the precursor lesion of esophageal adenocarcinoma, a tumor with increasing incidence and poor prognosis. The overall aim of the thesis was to assess risk and prognosis in patients with Barrett’s esophagus and esophageal adenocarcinoma. LÄS MER
5. Gastroesophageal reflux disease - complications and prognostic aspects
Sammanfattning : This thesis investigates several aspects on gastroesophageal reflux disease (GERD) and associated complications as Barrett’s esophagus and esophageal adenocarcinoma. I. To clarify the natural course of GERD, a pH-metry verified cohort was re-evaluated after 20 years. The course of GERD may well be progressive. LÄS MER