Sökning: "Androgen: genetics"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden Androgen: genetics.

1. 1. Cytogenetic and molecular analysis of chromosomal rearrangements associated with neuropsychiatric disorders

   Författare :Dmitry Tentler; Niels Tommerup; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Mental retardation; autism; Asperger syndrome; chromosomal rearrangement; Genetik; Clinical genetics; Klinisk genetik; Clinical Genetics; klinisk genetik;

   Sammanfattning : Genetic factors are important in the aetiology of neuropsychiatric disorders. Analysis of chromosomal abnormalities associated with these disorders may provide locus specific information for the identification of candidate genes and, subsequently, for our understanding of brain development and functioning. LÄS MER

3. 2. On the influence of serotonin- and sex steroid-related genetic variation on mood, anxiety, personality, autism and transsexualism

   Författare :Susanne Henningsson; Göteborgs universitet; []
   Nyckelord :serotonin; 5-HTTLPR; TPH2; 5-HT3; sex steroids; androgen receptor; estrogen receptor; genetics; gene-gene interaction; social phobia; anxiety; premenstrual dysphoric disorder; depression; personality; autism; transsexualism; amygdala; emotional perception; life events;

   Sammanfattning : Background: The neurotransmitter serotonin has been related to mood and anxiety, and variation in genes that encode important members of the serotonergic system may hence affect mood- and anxiety-related traits. Sex steroids influence brain development, and variation in genes encoding androgen and estrogen receptors, or enzymes needed for sex steroid synthesis, may be of importance for both personality traits and risk for psychiatric disorders. LÄS MER

4. 3. Studies of hyperandrogenicity and the metabolic syndrome in premenopausal women

   Författare :Fariba Baghaei; Göteborgs universitet; []
   Nyckelord :androgens; SHBG; HPA axis; abdominal obesity; insulin; HDL; metabolic syndrome; ovarian volume; PCOS; polymorphism; genetics; androgen receptor; estrogen receptor; aromatase;

   Sammanfattning : An androgenic sex hormone profile appears to be a typical feature of the metabolic syndrome (MetS) and a powerful risk factor for the development of type 2 diabetes in women. The causes of relative hyperandrogenicity (HA) are not clearly defined. LÄS MER

5. 4. Familial and Hereditary Prostate Cancer

   Författare :Ola Bratt; Urologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nephrology; Urology; screening; risk perception; hereditary; androgen receptor; genetics; Prostate cancer; epidemiology; Urologi; nefrologi;

   Sammanfattning : This thesis is based on research concerning epidemiological, clinical, and psychological aspects of familial and hereditary prostate cancer. Epidemiology: Male first-degree relatives of prostate cancer patients had a three-fold increased prostate cancer risk. LÄS MER

7. 5. Polymorphism in sex steroid-related genes. Effects on hormone levels and behavior

   Författare :Lars Westberg; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sex steroids; androgen receptor; estrogen receptor; progesterone receptor; polymorphism; genetics; association study; prolactin; personality; premenstrual dysphoric disorder; Parkinson s disease;

   Sammanfattning : Genetic factors are important for variations between individuals with respect to most humantraits and diseases. Sex steroids are of profound importance for reproduction, metabolism,cardiovascular function and bone formation. They are potent regulators of their ownsynthesis as well as of that of other hormones, including prolactin. LÄS MER