Sökning: "4RepCT"

Visar resultat 1 - 5 av 8 avhandlingar innehållade ordet 4RepCT.

1. 1. Investigating mucin interactions with diverse surfaces for biomedical applications

   Författare :Georgia Petrou; Thomas Crouzier; Anette Larsson; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mucus; mucin; protein adsorption; biomaterials; lubrication; mucoadhesion; 4RepCT; Bioteknologi; Biotechnology;

   Sammanfattning : Mucous membranes are covered with mucus, a viscoelastic hydrogel that plays an essential role in their protection from shear and pathogens. The viscoelasticity of mucus is owing to mucins, a group of densely glycosylated proteins. LÄS MER

3. 2. Expanded knowledge on silk assembly for development of bioactive silk coatings

   Författare :Linnea Nilebäck; My Hedhammar; Renko de Vries; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Recombinant spider silk; Self-assembly; Biomaterial; Implant coating; Functionalization; Multi-functional; Bioactive; Cell culture scaffold; Antibacterial; Bioteknologi; Biotechnology;

   Sammanfattning : Silk is a fascinating natural material made from proteins that self-assemble through structural rearrangements into one of the toughest materials known. As silk is protein-based, durable and elastic, it has many features that makes it suitable as a scaffold material for tissue engineering. LÄS MER

4. 3. Functionalization of spider silk with affinity and bioactive domains via genetic engineering for in vitro disease diagnosis and tissue engineering

   Författare :Naresh Thatikonda; My Hedhammar; Hanna Dams Kozlowska; KTH; []
   Nyckelord :affinity domains; artificial ECM; basic fibroblast growth factor; functionalization; mammalian cell culture; micro-and nano arrays; partial spider silk; single chain variable fragments; Bioteknologi; Biotechnology;

   Sammanfattning : In the recent past, spider silk has drawn significant attention from researchers mainly due to its distinguished mechanical strength, elasticity, biocompatibility and biodegradability. Technological advancements in genetic engineering have resulted in methods for creation of partial spider silk proteins. LÄS MER

5. 4. Recombinant spider silk for biomedical applications - from functionalizing surfaces of synthetic materials to in vitro modelling of tissues

   Författare :Christos Panagiotis Tasiopoulos; My Hedhammar; Antonella Motta; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; recombinant spider silk; surface functionalization; in vitro tissue models; membrane-based models; barrier tissues; cell co-culture; tissue engineering; Bioteknologi; Biotechnology;

   Sammanfattning : Spider silk is a natural protein-based material known for its medicinal use and remarkable mechanical properties. Structures made thereof are both strong and elastic and have been shown to be favorable matrices for tissue engineering. LÄS MER

7. 5. Engineering of Antibacterial Phage-Derived Proteins

   Författare :Fredrik Seijsing; Anders Nilsson; Yves Briers; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Protein engineering; endolysin; IgG; linker protein; chimeric protein; artificial opsonin; spider silk; antibacterial surface; bacteriophage; structure prediction; molekylär biovetenskap; Molecular Bioscience;

   Sammanfattning : The increasing threat of antibiotic resistance calls for the development of new treatment methods. Bacteriophages are interesting candidates since they can lyse bacteria with great efficiency. Bacteriophages produce enzymes called endolysins which break down the peptidoglycan in the cell wall at the end of the infection cycle. LÄS MER