Sökning: "monotopic membrane protein"
Visar resultat 1 - 5 av 6 avhandlingar innehållade orden monotopic membrane protein.
1. Exploring the Interplay of Lipids and Membrane Proteins
Sammanfattning : The interplay between lipids and membrane proteins is known to affect membrane protein topology and thus have significant effect (control) on their functions. In this PhD thesis, the influence of lipids on the membrane protein function was studied using three different membrane protein models. LÄS MER
2. Property-controlling Enzymes at the Membrane Interface
Sammanfattning : Monotopic proteins represent a specialized group of membrane proteins in that they are engaged in biochemical events taking place at the membrane interface. In particular, the monotopic lipid-synthesizing enzymes are able to synthesize amphiphilic lipid products by catalyzing two biochemically distinct molecules (substrates) at the membrane interface. LÄS MER
3. Intracellular vesicles induced by monotopic membrane protein in Escherichia coli
Sammanfattning : The monotopic membrane protein alMGS, a glycosyltransferase catalyzing glucolipid synthesis in Acholeplasma laidlawii, was overexpressed in Escherichia coli. Optimization of basic growth parameters was performed, and a novel method for detergent and buffer screening using a small size-exclusion chromatography was developed. LÄS MER
4. Taming the Griffin : Membrane interactions of peripheral and monotopic glycosyltransferases and dynamics of bacterial and plant lipids in bicelles
Sammanfattning : Biological membranes form a protective barrier around cells and cellular compartments. A broad range of biochemical processes occur in or at membranes demonstrating that they are not only of structural but also of functional importance. One important class of membrane proteins are membrane-associated glycosyltransferases. LÄS MER
5. Insight into 5-lipoxygenase biocatalysis and interaction with membrane components
Sammanfattning : Inflammation is one of the innate defence mechanisms exerted by the human body for protection and to initiate the healing process. Chronic inflammatory reactions can lead to several disease conditions like asthma, allergic rhinitis and rheumatoid arthritis. LÄS MER