Sökning: "membrane curvature"

Visar resultat 1 - 5 av 30 avhandlingar innehållade orden membrane curvature.

1. 1. Exploring the Interplay of Lipids and Membrane Proteins

   Författare :Candan Ariöz; Åke Wieslander; Daniel O. Daley; Malcolm East; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Membrane lipids; membrane proteins; anionic lipids; membrane remodeling; intracellular vesicles; model membrane systems; glycosyltransferase; Escherichia coli; lipid composition; fatty acid modification; membrane curvature; bacterial homeoviscous adaptation; Biochemistry; biokemi;

   Sammanfattning : The interplay between lipids and membrane proteins is known to affect membrane protein topology and thus have significant effect (control) on their functions. In this PhD thesis, the influence of lipids on the membrane protein function was studied using three different membrane protein models. LÄS MER

3. 2. Xanthophyll Cycle in the Light of Thylakoid Membrane Lipids - Membrane Packing, Curvature Elastic Stress and Enzyme Binding

   Författare :Anna Szilagyi; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; steroider; Lipids; steroids; membranes; Lipider; enzymologi; HPLC; laurdan; fluorescence spectroscopy; Proteins; enzymology; Proteiner; curvature elastic stress; enzyme binding; thylakoid membrane; membrane fluidity; lipid packing; histidine; VDE; zeaxanthin; xanthophyll cycle; mebran;

   Sammanfattning : The xanthophyll cycle involves the light-dependent and reversible conversion of violaxanthin to zeaxanthin. The enzyme, violaxanthin de-epoxidase (VDE) catalyses the conversion of violaxanthin to zeaxanthin, via the intermediate antheraxanthin. VDE is a membrane-hosted enzyme during its activity. LÄS MER

4. 3. A computational approach to curvature sensing in lipid bilayers

   Författare :Federico Elías-Wolff; Alexander Lyubartsev; Max Berkowitz; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; curvature sensing; membrane curvature; cardiolipin; amphipathic helix; symmetric multimers; lipid bilayer; molecular dynamics; Biophysics; biofysik;

   Sammanfattning : Local curvature is a key driving force for spatial organization of cellular membranes, via a phenomenon known as membrane curvature sensing, where the binding energy of membrane associated macromolecules depends on the local membrane shape. However, the microscopic mechanisms of curvature sensing are not well understood. LÄS MER

5. 4. Property-controlling Enzymes at the Membrane Interface

   Författare :Changrong Ge; Åke Wieslander; Marcelo E. Guerin; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; monotopic membrane protein; lipid-protein interaction; membrane curvature; glycosyltransferase; Rossmann fold; Biochemistry; Biokemi; biokemi; Biochemistry;

   Sammanfattning : Monotopic proteins represent a specialized group of membrane proteins in that they are engaged in biochemical events taking place at the membrane interface. In particular, the monotopic lipid-synthesizing enzymes are able to synthesize amphiphilic lipid products by catalyzing two biochemically distinct molecules (substrates) at the membrane interface. LÄS MER

7. 5. Optical Methods for Tympanic Membrane Characterisation : Towards Objective Otoscopy in Otitis Media

   Författare :Mikael Sundberg; Tomas Strömberg; Ton van Leeuwen; Linköpings universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Optical Methods; Spectroscopy; Surface Curvature; Monte Carlo; Tympanic Membrane; Otitis Media; Medical engineering; Medicinsk teknik;

   Sammanfattning : Otitis media, which is an upper respiratory tract infection that affect the middle ear, is the second most common disease in childhood, outnumbered in prevalence only by the common cold. Diagnosis of middle ear inflammation is often performed in the primary healthcare where the normal procedure involves anamnesis and physical examination of the tympanic membranes (TM) of the patient, usually be means of otoscopy. LÄS MER