Sökning: "virulence genes"

Visar resultat 21 - 25 av 159 avhandlingar innehållade orden virulence genes.

  1. 21. Regulatory pathways and virulence inhibition in Listeria monocytogenes

    Författare :Christopher Andersson; Jörgen Johansson; Debra Milton; Åke Forsberg; Claude Parsot; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Listeria monocytogenes; PrfA; ActA; infection; molekylärbiologi; Molecular Biology;

    Sammanfattning : Listeria monocytogenes is a rod-shaped Gram positive bacterium. It generally exist ubiquitously in nature, where it lives as a saprophyte. Occasionally it however enters the food chain, from where it can be ingested by humans and cause gastro-intestinal distress. In immunocompetent individuals L. LÄS MER

  3. 22. Genetic approaches towards understanding penumococcal virulence and biology

    Författare :Jenny Fernebro; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Streptococcus pneumoniae, the pneumococcus, is a major human pathogen giving rise to death and illness worldwide every year. It causes a wide variety of diseases, from normally harmless infections such as otitis media to potentially life-threatening systemic diseases such as pneumonia, meningitis and sepsis. LÄS MER

  4. 23. Modulators of Vibrio cholerae predator interaction and virulence

    Författare :Barbro Lindmark; Sun Nyunt Wai; Kristian Riesbeck; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vibrio cholerae; Caenorhabditis elegans; PrtV; outer membrane vesicles; non-O1 non-O139; serum resistance; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : Vibrio cholerae, the causal agent of cholera typically encodes two critical virulence factors: cholera toxin (CT), which is primarily responsible for the diarrhoeal purge, and toxin-co-regulated pilus (TCP), an essential colonisation factor. Nontoxigenic strains expressing TCP can efficiently acquire the CT gene through lysogenic conversion with CTXΦ, a filamentous phage that encodes CT and uses TCP as a receptor. LÄS MER

  5. 24. Surface antigens and virulence in Plasmodium falciparum malaria

    Författare :Johan Normark; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Plasmodium falciparum is an intracellular protozoan that may cause severe forms of malaria. It is a major world health hazard and reaps the highest toll among the children and pregnant mothers of the developing world. An Anopheles mosquito vector injects the pathogen when taking a blood meal. LÄS MER

  7. 25. Endothelial cytoadherence, rosetting and virulence in Plasmodium falciparum malaria

    Författare :Andreas Heddini; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Plasmodium falciparum; malaria; endothelial adhesion; erythrocyte rosetting; PECAM- 1 CID3 1; immunoglobulins; cerebral malaria; PfEMP- 1; var-genes;

    Sammanfattning : Excessive sequestration of Plasmodium falciparum-infected erythrocytes (pRBC) and uninfected erythrocytes directly blocks the microcirculation and precipitates severe symptoms from the affected organ and is thereby thought to be responsible for the severe complications which may occur during P. falciparum infection. LÄS MER