Sökning: "virulence genes"
Visar resultat 16 - 20 av 159 avhandlingar innehållade orden virulence genes.
16. A strategy to identify novel antimicrobial compounds : a bioinformatics and HTS approach
Sammanfattning : Bacterial infections are again becoming difficult to treat because the microbes are growing increasingly resistant to the antibiotics in use today. The need for novel antimicrobial compounds is urgent and to achieve this new targets are crucial. In this thesis we present a strategy for identification of such targets via a bioinformatics approach. LÄS MER
17. Regulation of Plasmodium falciparum virulence genes and immune response to surface antigens in placental malaria
Sammanfattning : Malaria infection caused by the parasite Plasmodium falciparum is a deadly torment, especially for young children and pregnant women residing in sub-Saharan Africa. Much of the parasites virulence is due to its ability to constantly vary the adhesive molecules expressed on the surface of infected red blood cells (iRBCs). LÄS MER
18. Bacterial colonization of the neonatal bowel and ileal pouch with focus on E. coli
Sammanfattning : The colonic microbiota is a source of inflammatogenic and potentially pathogenic bacteria, but also a source of immune maturation signals to the infant. Here, we have investigated the normal colonic microbiota, with focus on E. coli in Swedish and Pakistani newborn infants, as well as the microbiota of the ileo-anal pouch in colectomized patients. LÄS MER
19. The accessory gene regulator, agr, a system for coordinate control of virulence genes in Staphylococcus aureus
Sammanfattning : Bacterial pathogenicity is generally multifactorial, and genes encoding virulence factors are often subject to coordinate regulation. The regulating systems are supposed to adapt the production of virulence factors in response to changes in the environment during the process of infection. LÄS MER
20. Regulation of virulence gene expression in Staphylococcus aureus
Sammanfattning : The pathogenic bacterium Staphylococcus aureus has the ability to cause a wide variety of human diseases, ranging from superficial abscesses and wound infections to deep and systemic infections such as osteomyelitis, endocarditis and septicaemia. The ability to cause disease has been attributed to a large number of toxins and digesting enzymes as well as to proteins at the bacterial surface that bind various host molecules. LÄS MER
