Sökning: "vesicle trafficking"
Visar resultat 1 - 5 av 30 avhandlingar innehållade orden vesicle trafficking.
1. Exploring Cellular Dynamics : From Vesicle Tethering to Cell Migration
Sammanfattning : Cells in the body communicate with each other in order to cooperate efficiently. This communication is in part achieved by regulated secretion of signaling molecules, which when released from a cell may activate receptors present at the plasma membrane of an adjacent cell. Such signals affect both cell fate and behavior. LÄS MER
2. Proteostasis beyond chaperones - Auxiliary systems in the management of damaged proteins
Sammanfattning : Aging entails loss of functionality and increased risk of death, even for unicellular organisms, such as the yeast Saccharomyces cerevisiae. On a cellular level, aging is accompanied by an accumulation of harmful aging factors, e.g. damaged and aggregated proteins. LÄS MER
3. Components controlling vesicle trafficking and regulated exocytosis in pancreatic beta-cells
Sammanfattning : Regulated exocytosis is a sophisticated, well-organized and conserved multistage process underlying release of both neurotransmitters and hormones. Exocytosis is mediated by SNARE proteins that act at the center stage by forming a SNARE complex with the intrinsic capability to execute membrane fusion. LÄS MER
4. Membrane Stress and the Role of GYF Domain Proteins
Sammanfattning : Intracellular membrane trafficking is regulated by a large number of protein complexes and lipids. Blocking of trafficking disrupts normal membrane dynamics and causes membrane stress. LÄS MER
5. Organization of signaling networks during receptor-mediated membrane protein trafficking
Sammanfattning : The mechanisms by which receptor signals are organized in a synergic/hierarchical manner in time and space during regulation of integral membrane protein traffic remain a present challenge. The aim of this study was to address some critical aspects of these processes. LÄS MER