Sökning: "tumor growth"

Visar resultat 6 - 10 av 770 avhandlingar innehållade orden tumor growth.

  1. 6. The role of Shb in ES cell differentiation, angiogenesis and tumor growth

    Författare :Nina Funa; Michael Welsh; Leif Jansson; Lars Holmgren; Uppsala universitet; []
    Nyckelord :Cell biology; Shb; tyrosine kinase signaling; ES; endoderm; mesoderm; apoptosis; microvasculature; tumor growth; Cellbiologi;

    Sammanfattning : Shb is a ubiquitously expressed adaptor protein with the ability to bind several tyrosine kinase receptors and intracellular signaling proteins. Previous studies have implied a wide spectrum of Shb-mediated cellular responses, which motivated me to further investigate the role of Shb in differentiation and angiogenesis. LÄS MER

  3. 7. Monitoring of neuroendocrine tumor patients undergoing systemic therapies

    Författare :Olof Pettersson; Anders Sundin; Håkan Geijer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Therapy monitoring; NET; neuroendocrine tumor; computed tomography; CT; PRRT; 177Lu-DOTATATE; TGR; tumor growth rate; theranostics; DOTATOC-PET CT; Radiology; Radiologi; Endokrinologi och Diabetologi; Endocrinology and Diabetology; Oncology; Onkologi;

    Sammanfattning : Monitoring of neuroendocrine tumor (NET) patients undergoing systemic therapies is troublesome as biomarkers capable of detecting tumor responses have been difficult to establish. Changes in the sum of target lesion diameters are used to evaluate the effects of therapy according to the response evaluation criteria in solid tumors (RECIST 1.1). LÄS MER

  4. 8. Cellular, Molecular and Functional Characterization of the Tumor Suppressor Candidate MYO1C

    Författare :Kittichate Visuttijai; Afrouz Behboudi; Katarina Ejeskär; Anders Oldfors; Volker Haucke; Högskolan i Skövde; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MYO1C; myosin IC; tumor suppressor gene; cancer; tumor; PI3K AKT signaling; Medical sciences; Medicin; MYO1C; myosin IC; tumor suppressor gene; cancer; tumor; PI3K AKT signaling;

    Sammanfattning : Tumor suppressor genes play a role as a growth regulator and a gatekeeper of a cell. Their inactivation is often detected in malignant tumors. Identification of novel tumor suppressor gene candidates may help to further understand tumorigenesis and aid in the discovery of a new treatment leading toward cure of cancer. LÄS MER

  5. 9. Imaging the tumor microenvironment : the dynamics and modification of hypoxia

    Författare :Anna Ljungkvist; Peggy L. Olive; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiology; tumor microenvironment; double hypoxic marker method; proliferation; hypoxia; hypoxic half-life; Radiologisk forskning; Radiological research; Radiologisk forskning; diagnostisk radiologi; Diagnostic Radiology;

    Sammanfattning : The tumor vasculature is poor and heterogeneous which may result in inadequate oxygenation and changed energy status. In addition the balance between cell proliferation and the rate of cell death is disturbed, which results in tumor growth. LÄS MER

  7. 10. Growth factor signaling in the breast tumor microenvironment

    Författare :Matteo Bocci; Avdelningen för translationell cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; Tumor microenvironment; Angiogenesis; Cancer-associated fibroblasts; PDGF-C; ALK1;

    Sammanfattning : Cancer represents a collection of malignancies characterized by an aberrant expansion of cells. This unrestrained growth is the result of the acquisition of several pro-survival features and the evasion of cellular fail-safe mechanisms, collectively known as the hallmarks of cancer. LÄS MER