Sökning: "tularemia"

Visar resultat 16 - 20 av 24 avhandlingar innehållade ordet tularemia.

  1. 16. Dispersal of ticks and their microorganisms by African-Western Palaearctic migratory birds

    Författare :Tove Hoffman; Björn Olsen; Åke Lundkvist; Kenneth Nilsson; Johan Normark; Uppsala universitet; []
    Nyckelord :African-Western Palaearctic; migratory birds; Ixodidae; Hyalomma rufipes; Ixodes; Alkhurma hemorrhagic fever virus; Anaplasma phagocytophilum; Francisella; Midichloria; Rickettsia aeschlimannii; PCR; microfluidic qPCR; metagenomics; Biologi; Biology;

    Sammanfattning : In Europe, tick-borne diseases are the most widespread and common vector-borne diseases and their geographical distribution is increasing. The dispersal of ticks depends on the movements of their vertebrate hosts. Avian hosts are more likely to be involved in long-distance range expansion of ticks due to their migration pattern. LÄS MER

  3. 17. Francisella tularensis infection induces macrophage cell death

    Författare :Xin-He Lai; Erik Kihlström; Umeå universitet; []
    Nyckelord :klinisk bakteriologi; Clinical Bacteriology;

    Sammanfattning : Francisella tularensis, the causative agent of tularemia, is a potent human and animal pathogen. Its principal survival mechanism is rapid intracellular multiplication. LÄS MER

  4. 18. Reactive oxygen and nitrogen in host defence against Francisella tularensis

    Författare :Helena Lindgren; Anders Sjöstedt; Tommy Sundquist; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Francisella tularensis; inducible nitric oxide synthase; phagocyte oxidase; macrophages; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; klinisk bakteriologi; Clinical Bacteriology;

    Sammanfattning : Francisella tularensis, the causative agent of tularemia, is a potent human and animal pathogen. Initially upon infection of the host, intramacrophage proliferation of F. tularensis occurs but after activation of the acquired host immunity, the phagocytes become activated to kill the bacterium. In my thesis, I focused on mechanisms utilized by F. LÄS MER

  5. 19. The Francisella pathogenicity island : its role in type VI secretion and intracellular infection

    Författare :Lena Meyer; Anders Sjöstedt; Siobhan C. Cowley; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Francisella; FPI; Type VI Secretion; Igl; DotU; VgrG; Pdp; microinjection; phagosomal escape; intracellular replication; Clinical Bacteriology; klinisk bakteriologi;

    Sammanfattning : Intracellular bacteria have developed various mechanisms to enter and persist in host cells and, at the same time, to evade the host immune response. One such pathogen is Francisella tularensis, the etiological agent of tularemia. LÄS MER

  7. 20. Effects of Francisella tularensis infection on macrophage intracellular signaling

    Författare :Maxim Telepnev; Agneta Richter-Dalfors; Umeå universitet; []
    Nyckelord :Clinical Bacteriology; klinisk bakteriologi;

    Sammanfattning : Microbes contain a number of structural components, also known as pathogen associated molecular patterns (PAMP), which can be recognized by the host defense system. The PAMP serve as ligands for Toll-like receptors (TLR) expressed on phagocytic cells. LÄS MER