Sökning: "tetrahydroisoquinoline"

Hittade 3 avhandlingar innehållade ordet tetrahydroisoquinoline.

  1. 1. Synthesis Towards Biologically Active Natural Products

    Författare :Rikard Larsson; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Transtaganolide; basiliolide; natural product; total synthesis; biomimetic; Thapsia; Diels-Alder; Ireland-Claisen; Pictet-Spengler; tetrahydroisoquinoline; indole;

    Sammanfattning : In 2005 two research groups independently reported the isolation of a series of structurally intriguing C-19 terpenolides from the plants Thapsia transtagana and Thapsia garganica. The compounds were shown to be potent inhibitors of the sarco/endoplasmic reticulum Ca2+-ATPases. LÄS MER

  3. 2. SAR Studies of Capsazepinod Bronchodilators. The A-ring and the Coupling region

    Författare :Maria Dalence; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; COPD; Asthma; Capsazepine; Bronchodilators; Organic chemistry; SAR studies; Organisk kemi;

    Sammanfattning : Bronchoconstriction is a hallmark in respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD). Current therapies use bronchodilating agents in order to control the exacerbations produced by limited airflow and improve the quality of life of patients suffering from these diseases. LÄS MER

  4. 3. SAR studies of Capsazepinoid Bronchodilators The B-ring and the C-region

    Författare :Magnus Berglund; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organisk kemi; Organic chemistry; bronchodilator; Capsazepine; structure activity relationship;

    Sammanfattning : Capsazepine and similar compounds, capsazepinoids, were shown to be general inhibitors of agonist (leukotriene D4, histamine, acetylcholine, prostaglandin D2) evoked constriction of human small airway preparations. The mechanism of action remains to be elucidated, but established bronchodilator principles, e.g. LÄS MER