Sökning: "Bronchodilators"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet Bronchodilators.

  1. 1. SAR Studies of Capsazepinod Bronchodilators. The A-ring and the Coupling region

    Författare :Maria Dalence; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; COPD; Asthma; Capsazepine; Bronchodilators; Organic chemistry; SAR studies; Organisk kemi;

    Sammanfattning : Bronchoconstriction is a hallmark in respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD). Current therapies use bronchodilating agents in order to control the exacerbations produced by limited airflow and improve the quality of life of patients suffering from these diseases. LÄS MER

  3. 2. SAR studies of Capsazepinoid Bronchodilators The B-ring and the C-region

    Författare :Magnus Berglund; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organisk kemi; Organic chemistry; bronchodilator; Capsazepine; structure activity relationship;

    Sammanfattning : Capsazepine and similar compounds, capsazepinoids, were shown to be general inhibitors of agonist (leukotriene D4, histamine, acetylcholine, prostaglandin D2) evoked constriction of human small airway preparations. The mechanism of action remains to be elucidated, but established bronchodilator principles, e.g. LÄS MER

  4. 3. Immunopathological and Structural Alterations in Difficult to Control Asthma

    Författare :Anders Bergqvist; Luftvägsinflammation; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Severe asthma; bronchial thermoplasty; airway smooth muscle; neuroendocrine cells; inflammation; immune cells; remodelling;

    Sammanfattning : Asthma is a chronic respiratory disorder affecting an estimated 300 million people worldwide. Most patients with asthma can be controlled with bronchodilators and low to moderate dose inhaled corticosteroids. However, an estimated 5-10% of the population presents a more troublesome disease, often referred to as severe asthma. LÄS MER

  5. 4. Bronchial hyperresponsiveness of ß-adrenoceptor agonists and antagonists in guinea pig airways

    Författare :Fredrik Johansson; Sven-Erik Dahlén; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Asthma is one of the most common diseases in the industrialised countries. The underlying mechanisms are complex and still not fully understood although inflammation of the airways plays an important role. LÄS MER

  7. 5. Inhaled pharmacological treatment and critical inhaler technique errors in patients with chronic obstructive pulmonary disease

    Författare :Johanna Sulku; Elisabet I. Nielsen; Alf Tunsäter; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic obstructive pulmonary disease; COPD; critical inhaler technique error; pharmacological treatment; ICS; inhaled corticosteroid; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease characterised by persistent respiratory symptoms and a high risk of exacerbations. Preventive and maintenance pharmacological treatment is primarily administered through handheld inhalers, which are available in several different device-drug combinations. LÄS MER