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Visar resultat 1 - 5 av 20 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Heme-copper oxidases and nitric oxide : Reaction mechanisms and supercomplex formation

    Författare :Ingrid Albertsson; Pia Ädelroth; Alessandro Giuffrè; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Heme-copper oxidase; nitrite reductase; nitric oxide reductase; nitric oxide; supercomplex; Paracoccus denitrificans; denitrification pathway; proton transfer pathway; C-type oxidase; Helicobacter pylori; Biochemistry; biokemi;

    Sammanfattning : In the denitrification process where nitrate is stepwise reduced to nitrogen gas, the toxic molecule nitric oxide (NO) is formed as an intermediate. Nitric oxide is produced by the enzyme cd1 Nitrite reductase (cd1NiR) by reduction of nitrite and is later reduced to nitrous oxide by nitric oxide reductase (cNOR). LÄS MER

  2. 2. Respiration in Actinobacteria : Structure, function and inhibition of the III2IV2 supercomplex

    Författare :Sylwia Król; Peter Brzezinski; Dirk Bald; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bioenergetics; structural biology; electron transport chain; respiratory supercomplex; electron transfer; proton transfer; biokemi; Biochemistry;

    Sammanfattning : The final step of aerobic respiration, oxidative phosphorylation, combines the activities of the electron transport chain and of ATP synthase. The electron transport chain is composed of membrane-bound energy transducers, which are organized in supramolecular assemblies known as respiratory supercomplexes. LÄS MER

  3. 3. Prokaryotic respiratory supercomplexes : Studies of interactions between complexes III and IV

    Författare :Olga Stah; Pia Ädelroth; Petra Hellwig; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; bioenergetics; membrane protein; bacterial respiration; electron transport chain; supercomplex; cytochrome c oxidase; membrane-anchored cytochrome c; cytochrome bc1 complex; electron transfer; proton transfer; time-resolved spectroscopy; apoptosis; biokemi; Biochemistry;

    Sammanfattning : Respiratory processes for cellular energy conversion are carried out by the membrane-associated enzymes of the electron transfer chain (ETC). In recent years there has been emerging data showing that the members of the ETC organize into higher-level assemblies called supercomplexes (SCs) whose functional relevance is not yet fully understood. LÄS MER

  4. 4. Structural characterisation of mitochondrial macromolecular complexes using cryo-EM : Mitoribosome biogenesis and respiratory chain supercomplex

    Författare :Sorbhi Rathore; Martin Ott; Daniel Wilson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; mitoribosome biogenesis; mitoribosome assembly factors; yeast respiratory supercomplexes; single particle electron cryo-microscopy; cryo-EM sample preparation; Biochemistry; biokemi;

    Sammanfattning : Mitochondria, popularly known as powerhouse of the cell, contain specialised mitoribosomes that synthesise essential membrane proteins. These essential proteins are required to form enzyme complexes, which carry out the process of oxidative phosphorylation (OXPHOS). LÄS MER

  5. 5. Wiring Components of the Respiratory Chain : Modulation of the Respiratory Chain in Yeast and Bacteria

    Författare :Jacob Schäfer; Peter Brzezinski; Dennis Winge; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cytochrome c oxidase; Electron transfer; Membrane protein; Ligand; Kinetics; Mechanism; Rcf1; Cytochrome c; Respiratory supercomplex; Cryo-electron microscopy; Biochemistry; biokemi;

    Sammanfattning : The enzyme complexes of the respiratory chain are organized in supramolecular assemblies, so-called respiratory supercomplexes. In the yeast Saccharomyces cerevisiae, these supercomplexes consist of two copies of complex III (bc1 complex) and one or two copies of complex IV (cytochrome c oxidase, CytcO). LÄS MER