Sökning: "Daniel Wilson"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Daniel Wilson.

1. 1. Holographic Wilson Loops : Quantum String Corrections

   Författare :Daniel Ricardo Medina Rincon; Konstantin Zarembo; Gianluca Grignani​; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Gauge-string correspondence; AdS CFT; Wilson loops; String theory; Theoretical Physics; Teoretisk fysik;

   Sammanfattning : The gauge-string duality has been one of the most exciting areas in theoretical physics as it connects strongly coupled field theories with weakly interacting strings. The present thesis concerns the study of Wilson loops in this correspondence. LÄS MER

3. 2. Molecular mechanisms of nerve-tumor interactions : the intersection of cancer and neurodevelopment

   Författare :Luz Maria Gonzalez-Castrillon; Sara I Wilson; Daniel Öhlund; Nisha D’Silva; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Perineural invasion; cancer; PDAC; axonogenesis; neurodevelopment; spinal cord; axon guidance; bioinformatics.; biomedical laboratory science; biomedicinsk laboratorievetenskap;

   Sammanfattning : A wide range of cancers throughout the body are characterized by high nerve density and invasion of cancer cells within the nerves, a process called perineural invasion (PNI). Work in the field has shown that blocking nerves in organs with tumors leads to improved disease outcomes suggesting that finding ways to block tumor nerves could lead to new treatment approaches. LÄS MER

4. 3. Dynamics of peptide chains during co-translational translocation, membrane integration & domain folding

   Författare :Rickard Hedman; Gunnar von Heijne; Daniel N. Wilson; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ribosome; membrane integration; translocation; folding; arrest peptide; SecM; Biochemistry; biokemi;

   Sammanfattning : The biosynthesis of proteins occurs at the ribosomes, where amino acids are linked together into linear chains. Nascent protein chains may undergo several different processes during their synthesis. Some proteins begin to fold, while others interact with chaperones, targeting factors or processing enzymes. LÄS MER

5. 4. Characterizing Elongation of Protein Synthesis and Fusidic Acid Resistance in Bacteria

   Författare :Srihari Nagendra Ravi Kiran Koripella; Suparna Sanyal; Daniel Wilson; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ribosome; Elongation factor-G; FusB; GTP; Staphylococcus aureus; Escherichia coli and Fusidic acid; Molecular Biology; Molekylärbiologi;

   Sammanfattning : Protein synthesis is a highly complex process executed by the ribosome in coordination with mRNA, tRNAs and translational protein factors. Several antibiotics are known to inhibit bacterial protein synthesis by either targeting the ribosome or the proteins factors involved in translation. LÄS MER

7. 5. Structural characterisation of mitochondrial macromolecular complexes using cryo-EM : Mitoribosome biogenesis and respiratory chain supercomplex

   Författare :Sorbhi Rathore; Martin Ott; Daniel Wilson; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; mitoribosome biogenesis; mitoribosome assembly factors; yeast respiratory supercomplexes; single particle electron cryo-microscopy; cryo-EM sample preparation; Biochemistry; biokemi;

   Sammanfattning : Mitochondria, popularly known as powerhouse of the cell, contain specialised mitoribosomes that synthesise essential membrane proteins. These essential proteins are required to form enzyme complexes, which carry out the process of oxidative phosphorylation (OXPHOS). LÄS MER