Sökning: "structure-activity-relationship"
Visar resultat 1 - 5 av 82 avhandlingar innehållade ordet structure-activity-relationship.
1. Cyclic sulfamides as HIV-1 protease inhibitors : Synthesis, X-ray structure analysis and structure-activity relationship
Sammanfattning : Human Immunodeficiency Virus (HIV) is the causative agent of Acquired Immune Deficiency Syndrome (AIDS). Inhibition of HIV-1 protease leads to immature and non-infectious viral particles. The synthesis of a number of cyclic HIV-1 protease inhibitors and the subsequent evaluation in an enzyme assay is presented in this thesis. LÄS MER
2. In silico tools in risk assessment : of industrial chemicals in general and non-dioxin-like PCBs in particular
Sammanfattning : Industrial chemicals in European Union produced or imported in volumes above 1 tonne annually, necessitate a registration within REACH. A common problem, concerning these chemicals, is deficient information and lack of data for assessing the hazards posed to human health and the environment. LÄS MER
3. Adrenergic agonists and antagonists : structure-activity relationship studies of the side chains of arylethanolamines and aryloxypropanolamines
Sammanfattning : .... LÄS MER
4. Synthesis and Structure-Activity Relationship. Studies of Non-Peptidic Urotensin II Receptor Agonists
Sammanfattning : .... LÄS MER
5. Synthesis and structure activity relationship studies of non-nucleoside HIV-1 reverse transcriptase inhibitors
Sammanfattning : HIV-1 reverse transcriptase (RT) is a target for anti-HIV chemotherapy. A series of PETT PhenylEthylThiazoleThiourea) non-nucleoside HIV-1 RT inhibitors were synthesised. All compounds were tested in an HIV-1 RT enzyme assay, and in cell culture using MT-4 cells and wild-type virus. LÄS MER
