Sökning: "streptococcal infection"

Visar resultat 6 - 10 av 38 avhandlingar innehållade orden streptococcal infection.

  1. 6. Bacterial virulence or exorbitant host response? On innate immunity against the streptococcal M1 protein

    Författare :Sandra Persson; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skin infection; Streptococcus pyogenes; M1 protein; Innate Immunity; Host response; Virulence factor; Neutrophil recruitment; Heparin-binding protein HBP ; Leptospirosis;

    Sammanfattning : Bacterial infection is inevitable throughout a lifetime. What differs between mild andserious infections is the pathogen responsible and how the host immune systemresponds to it. A fundamental role to prevent infection is a proper physical barrier such as the skin and mucosa. LÄS MER

  3. 7. Streptococcal virulence and the coagulation system

    Författare :Kristofer Wollein Waldetoft; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Streptococci; virulence; coagulation; intrinsic pathway; evolution;

    Sammanfattning : This thesis explores streptococcal virulence from both mechanistic and evolutionary perspectives, where the mechanistic studies focus on interactions with the human coagulation system. We describe interactions between streptococcal surface proteins and components of the intrinsic pathway of coagulation and the kallikrein-kinin system in human plasma, as well as to how these surface proteins are produced in different growth phases. LÄS MER

  4. 8. Molecular studies on streptococcal surface proteins

    Författare :Johan Waldemarsson; Avdelningen för medicinsk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nonimmunodominance; vaccine; camouflaging; Streptococcus agalactiae; leucine-rich repeat; Streptococcus pyogenes; alpha; fibrinogen; M protein; surface proteins; Rib;

    Sammanfattning : Streptococcus agalactiae and Streptococcus pyogenes are two related human pathogens causing different diseases. This thesis focuses on a number of surface proteins expressed by S. agalactiae and S. pyogenes and, more specifically, the molecular and biological characterization of these proteins. LÄS MER

  5. 9. Group B streptococcal infections in neonates : Clinical and pathogenic aspects

    Författare :Jan Källman; Leif Gothefors; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Clinical and pathogenic aspects of Group B streptococci (GBS), as a major pathogen responsible of invasive disease in newborn infants, were investigated.Cases of neonatal septicaemia during 1981-1994 were studied at Orebro Medical Centre Hospital. 132 children ful1filled laboratory and clinical criteria for neonatal septicaemia. LÄS MER

  7. 10. Streptococcal cell surface proteins : structure and gene characterisation

    Författare :Viatcheslav Katerov; Avdelningen för medicinsk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mikrobiologi; mycology; virology; bacteriology; virologi; mykologi; Microbiology; bakteriologi;

    Sammanfattning : Streptococcus pyogenes (group A streptococci, GAS) is a potent human pathogen known to express a number of cell surface associated virulence factors. It is an established fact that these different surface proteins play an important role during infection. LÄS MER