Sökning: "retinopathy"

Visar resultat 21 - 25 av 96 avhandlingar innehållade ordet retinopathy.

  1. 21. Long term complications in juvenile diabetes mellitus

    Författare :Maria Nordwall; Johnny Ludvigsson; Knut Borch-Johnsen; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diabetes mellitus type 1; diabetic retinopathy; diabetic nephropathy; diabetic neuropathy; epidemiology; C-peptide; Diabetology; Diabetologi;

    Sammanfattning : Background/aim. The incidence of microvascular complications has been reported to be unchanged the last decades. However, in randomized clinical trials it has been shown that improved metabolic control can reduce the development of long term complications. LÄS MER

  3. 22. Conditional targeting of the PDGF-B gene

    Författare :Maria Enge; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gene targeting; Cre loxP; PDGF; pericytes; diabetic retinopathy; brain injury; neurons;

    Sammanfattning : Platelet derived growth factors (PDGF) are known as mitogens for fibroblasts, smooth muscle cells (SMC) and glia cells in culture. Previous in vivo analyses have shown that PDGF-B is necessary for normal embryonic development and life after birth, but the relative importance of the various cellular sources of PDGF-B during development has not been clarified. LÄS MER

  4. 23. Hypoglycaemia: Studies on central and peripheral nerve function

    Författare :Bodil Eckert; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrinology; severe retinopathy.; QT interval; Type 1 diabetes; cerebral blood flow; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : Hypoglycaemia is an acute complication to insulin-treatment in type 1 diabetes mellitus, which affects many physiological parameters, deteriorates the cognitive function, and may lead to death. The aim of this thesis was to study nerve function, cognitive function and cerebral blood flow during and after hypoglycaemia in healthy subjects and to study certain aspects of a fall in blood glucose in patients with type 1 diabetes mellitus. LÄS MER

  5. 24. ENDOTHELIAL- EPITHELIAL INTERACTIONS Blood vessels friends or foes?

    Författare :Fredrik Wolfhagen Sand; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; blood vessels; pancreas; endoderm development; S1P1; N-CAM; diabetic retinopathy; diabetes; tubulogenesis; Cdc42;

    Sammanfattning : Diabetes affects enormous amounts of patients. In type 1 diabetes the insulin producing β cells in the islet of Langerhans are destroyed by the immune system. The β cells, which are located in the pancreas, regulate blood glucose levels. The lack of insulin production requires administration of insulin. LÄS MER

  7. 25. Macro- and microvascular complications of diabetes: Studies on NFAT (Nuclear Factor of Activated T-cells) as a novel target for the treatment of atherosclerosis and vascular dysfunction in diabetes

    Författare :Fabiana Blanco; Diabetiska komplikationer; []
    Nyckelord :NFAT; VSMCs; Diabetes; Hyperglycemia; Aterosclerosis; Diabetic retinopathy; Oxidative stress;

    Sammanfattning : Diabetes is associated with devastating chronic complications including coronary heart disease and stroke (macrovascular complications) as well as microvascular disorders leading to damage of the small vessels and the development of retinopathy, nephropathy and neuropathy. The underlying pathogenesis is not clear, but hyperglycemia has been identified as an important risk factor. LÄS MER