Sökning: "S1P1"

Hittade 3 avhandlingar innehållade ordet S1P1.

  1. 1. ENDOTHELIAL- EPITHELIAL INTERACTIONS Blood vessels friends or foes?

    Författare :Fredrik Wolfhagen Sand; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; blood vessels; pancreas; endoderm development; S1P1; N-CAM; diabetic retinopathy; diabetes; tubulogenesis; Cdc42;

    Sammanfattning : Diabetes affects enormous amounts of patients. In type 1 diabetes the insulin producing β cells in the islet of Langerhans are destroyed by the immune system. The β cells, which are located in the pancreas, regulate blood glucose levels. The lack of insulin production requires administration of insulin. LÄS MER

  3. 2. The role of N-cadherin and S1P/S1P1 in pancreas development

    Författare :Jenny Johansson; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Organogenesis of epithelial organs requires interaction between epithelial and mesenchymal tissues. During pancreas development, mesenchyme-derived structures induce specification, growth and differentiation of pancreatic epithelial cells. LÄS MER

  4. 3. On the stimulatory effect of microglial cells on angiogenesis

    Författare :Simin Rymo; Göteborgs universitet; []
    Nyckelord :microglia; angiogenesis; aortic ring;

    Sammanfattning : ABSTRACT Angiogenesis, the process by which new vessels sprout from pre-existing vessels, is fundamental to development, tissue growth and repair. The main aim of this thesis was to investigate the role of microglia on angiogenesis. We adapted the rat ex vivo/in vitro aortic ring model to the mouse in a 3-D culture system. LÄS MER