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Visar resultat 1 - 5 av 6 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Extreme hemodilution: Effects of inhalation anesthetics, hypoxia, and blood loss. An Experimental study in pigs

    Författare :Henning Schou; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anaesthesiology; oxygen saturation.; blood volume; coronary circulation; blood lactate; oxygen uptake; Anemia; oxygen delivery; intensive care; Anestesiologi; intensivvård;

    Sammanfattning : Hemodilution reduces the need for blood transfusion and hereby the risk for transmission of infectious agents. The present study investigated effects on systemic and myocardial circulation and oxygenation, and blood lactate concentrations; induced by nitrous oxide, isoflurane, hypoxia, and uncompensated blood loss, in pigs hemodiluted to a hematocrit of 11%. LÄS MER

  3. 2. Evaluation and development of a capnodynamic method for estimation of pulmonary blood flow in a porcine model

    Författare :Caroline Hällsjö Sander; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :cardiac output;

    Sammanfattning : Effective pulmonary blood flow (EPBF) i.e. cardiac output (CO) minus shunt flow could be estimated by a capnodynamic equation. Via introduction of short pauses in the ventilatory pattern the required alterations of carbon dioxide are induced. LÄS MER

  4. 3. The role of the endothelin system in experimental acute lung injury : with special reference to the formation of extra-vascular lung water

    Författare :Patrik Rossi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Acute lung injury; endothelin-1; extra-vascular lung water; pulmonary capillary pressure; sepsis; pulmonary edema; endotoxin;

    Sammanfattning : Acute lung injury is a major clinical challenge in the intensive care unit. Sepsis is the most frequent underlying cause of this pulmonary syndrome, which contains inflammation-induced diffuse alveolar damage and early stage high permeability edema. LÄS MER

  5. 4. Effects of gravity and posture on the human lung

    Författare :Malin Rohdin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Acceleration; cardiac output; cardiogenic oscillations; closing volume; gas exchange; heart I-ate; human centrifuge; hypergravity; lung diffusing capacity; prone posture; pulmonary-capillary blood volume; rebreathing; single-breath washout; supine;

    Sammanfattning : The presence of the gravitational force at the surface of Earth affects all of the organ systems in landliving creatures. The function of the lung is particularly susceptible to changes in the direction and magnitude of gravity because of the elastic structure of this organ. LÄS MER

  7. 5. Transvascular fluid dynamics in the pulmonary vasculature in horses at rest and during exercise

    Författare :Modest Vengust; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Maximal exercise results in a marked increase in cardiac output (Q) with consequent adaptations in pulmonary macro- and microvasculature. These adaptations change pulmonary hemodynamics and increase fluid and solute movement between the pulmonary circulation and the pulmonary interstitium (across the lung). LÄS MER