Sökning: "prostate specificity"

Visar resultat 11 - 15 av 31 avhandlingar innehållade orden prostate specificity.

  1. 11. Human glandular kallikrein 2 (hK2) in prostate cancer: Clinical and Methodological studies

    Författare :Charlotte Becker; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; screening; prostate cancer; PSA; Human glandular kallikrein; hK2; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Sammanfattning : Human glandular kallikrein 2 (hK2) is a predominantly prostate produced protein with many similarities to prostate-specific antigen (PSA). Just like for PSA elevated levels of hK2 can be found in men with protate cancer. We created an assay where hK2 in serum could reliably and with negligible cross-reactivity with PSA, be measured down to 0. LÄS MER

  3. 12. Aspects of PET-CT in prostate cancer. Protocol optimization, diagnostic accuracy, and dosimetry

    Författare :Mimmi Bjöersdorff; Malmö Nuklearmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PET-CT; Prostatacancer; [18F]FCH; [18F]PSMA-1007; optimering; diagnostisk noggrannhet; dosimetri; PET-CT; Prostate Cancer; [18F]FCH; [18F]PSMA-1007; Optimization; Diagnostic accuracy; Dosimetric;

    Sammanfattning : The PET-CT imaging modality is based on positron emission tomography combined with computed tomography. Before a PET-CT examination, a radioactive tracer (also called a radiopharmaceutical) is intravenously injected into the patient. PET technology images the distribution of this tracer element by detecting the decay. LÄS MER

  4. 13. The diagnostic performance of prostate-specific antigen (PSA) in early detection of prostate cancer : considerations of sensitivity, specificity, lead-time and survival

    Författare :Magnus Törnblom; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :PSA; free PSA; prostate cancer; sensitivity; specificity; lead-time; survival; epidemiology;

    Sammanfattning : Background: Prostate cancer (PC) is the most common form of cancer, as well as the single major cause of cancer-related mortality among Swedish males. Recent reports indicate that screening of the serum levels of prostate-specific antigen (PSA) in asymptomatic men may result in decreases in both the incidence of metastatic disease and PC-specific mortality. LÄS MER

  5. 14. Biopsies, diagnosis and prognosis in prostate cancer

    Författare :Lars Häggarth; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Prostate cancer is the third most common cancer in men worldwide, and poses a challenge both for patients and health care systems. Many aspects of prostate cancer are controversial, from screening for early detection to the concept of insignificant cancer that does not need curative treatment. LÄS MER

  7. 15. Miniaturised and Quantitative Techniques Targeting Prostate Cancer

    Författare :Kerstin Järås; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The prostate-specific antigen (PSA) test used in the clinic today has been subjected to suspicions regarding specificity and sensitivity, since cases of benign prostatic hyperplasia or prostatitis are hard to distinguish from those with prostate cancer. This thesis is based upon five original papers describing efforts to develop antibody microarrays enabling improved diagnostic prostate cancer analysis. LÄS MER