Sökning: "persson 2009"

Visar resultat 1 - 5 av 58 avhandlingar innehållade orden persson 2009.

  1. 1. Temporal Modulation in Fluorescence Spectroscopy and Imaging for Biological Applications

    Författare :Gustav Persson; Jerker Widengren; Jörg Enderlein; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; fluorescence; spectroscopy; microscopy; modulated excitation; intensity modulation; fluorescence correlation spectroscopy; transient states; molecular kinetics; Physics; Fysik;

    Sammanfattning : This thesis explores the benefits of intensity modulation for the purpose of extending the range of applications of fluorescence spectroscopy and imaging in cellular and molecular biology and medicine. Long-lived transient states of fluorescent molecules can, because of their long lifetimes, be used to detect subtle changes in the microenvironment of the molecule. LÄS MER

  3. 2. Plant-Derived Substances and Cardiovascular Diseases : Effects of Flavonoids, Terpenes and Sterols on Angiotensin-Converting Enzyme and Nitric Oxide

    Författare :Ingrid Persson; Rolf G.G. Andersson; Lars Bohlin; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Diet has for many years been known to play a key role in the development of chronic diseases. There are clear associations between consumption of vegetables, fruits and berries, and risk of cardiovascular diseases, the number one cause of death in the world. LÄS MER

  4. 3. Development of molecular recognition by rational and combinatorial engineering

    Författare :Andreas Jonsson; Stefan Ståhl; Mats Persson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Affibody molecule; albumin binding domain; protein engineering; phage display; amyloid beta peptide; TNF; HSA; Molecular biology; Molekylärbiologi;

    Sammanfattning : Combinatorial protein engineering, taking advantage of large libraries of protein variants and powerful selection technology, is a useful strategy for developing affinity proteins for applications in biotechnology and medicine. In this thesis, two small affinity proteins have been subjected to combinatorial protein engineering to improve or redirect the binding. LÄS MER

  5. 4. Protein based approaches to understand and prevent contagious bovine pleuropneumonia

    Författare :Carl Hamsten; Anja Persson; Joachim Frey; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; CBPP; Mycoplasma mycoides subsp. mycoides small colony type; humoral immune responses; recombinant surface proteins; ELISA; subunit vaccine; suspension bead array; Bioengineering; Bioteknik;

    Sammanfattning : Contagious bovine pleuropneumonia (CBPP) is a severe infectious disease caused by Mycoplasma mycoides subsp. mycoides small colony type (M. mycoides SC) and is a vast problem in Africa. LÄS MER

  7. 5. Staphylococcal surface display in directed evolution

    Författare :Nina Kronqvist; Stefan Ståhl; Mats A. A. Persson; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; affibody; combinatorial library; directed evoluation; Gram-positive bacteria. protein engineering; Bioengineering; Bioteknik;

    Sammanfattning : Engineered affinity proteins have together with naturally derived antibodies becomeindispensable tools in many areas of life-science and with the increasing number ofapplications, the need for high-throughput methods for generation of such different affinityproteins is evident. Today, combinatorial protein engineering is the most successful strategy toisolate novel non-immunoglobulin affinity proteins. LÄS MER