Sökning: "partial least squares"

Visar resultat 16 - 20 av 112 avhandlingar innehållade orden partial least squares.

  1. 16. In silico tools in risk assessment : of industrial chemicals in general and non-dioxin-like PCBs in particular

    Författare :Mia Stenberg; Patrik Andersson; Miriam Jacobs; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemometrics; industrial chemicals; in silico tools; molecular descriptors; non-dioxin-like PCBs; partial least-squares PLS ; principal component analysis PCA ; quantitative structure-activity relationship QSAR ; REACH; risk assessment RA ; statistical molecular design; structure-activity relationship SAR ;

    Sammanfattning : Industrial chemicals in European Union produced or imported in volumes above 1 tonne annually, necessitate a registration within REACH. A common problem, concerning these chemicals, is deficient information and lack of data for assessing the hazards posed to human health and the environment. LÄS MER

  3. 17. Practical application of machine learning for analyses of biological matrices and environmental phenomena

    Författare :Alexandra Walsh; Göteborgs universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Machine learning; Surface enhanced Raman spectroscopy; Acute lymphatic leukaemia; Volatile halogenated organic carbons; Marine algae; Doxorubicin; Principal component analysis; Multivariate statistics; Design of experiments; Waterlogged archaelogical wood; Transposed orthogonal partial least squares;

    Sammanfattning : This thesis presents research aimed at forwarding an understanding of machine learning methods as a method of studying complex matrices and environmental phenomena. A number of machine learning methods in the form of linear projection algorithms and statistical experimental designs were applied for qualitative analysis of different matrices. LÄS MER

  4. 18. Signal identification for visual electrophysiological recordings. A comparison of signal analysis techniques and their application to clinical electrophysiology of vision

    Författare :Thomas Wright; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Visual Electrophysiology; Signal detection; Signal-to-Noise Ratio; multivariate analysis; spatial-temporal partial least-squares;

    Sammanfattning : Aims: The aim of this thesis was to investigate the use of objective methods for the analysis of visual electrophysiological recordings. Specifically can signal identification algorithms identify electrophysiological signals and can they be applied to improve clinical testing and analysis? Methods: Automated signal identification algorithms were applied to multifocal electroretinogram (mfERG) and visual evoked potential (VEP) recordings. LÄS MER

  5. 19. Characterisation of mammalian cell culture processes with NIR spectroscopy

    Författare :Per Sivertsson; KTH; []
    Nyckelord :near-infrared NIR spectroscopy; cell culture; mammalian cell culture; characterisation; glucose; lactate; ammonia; cell content; viability; multivariate analysis; principal component analysis PCA ; partial least squares regression PLS ; score plo;

    Sammanfattning : The importance of recombinant proteins produced by mammaliancell culture has increased dramatically due to the discoveriesin the field of recombinant biotechnology. Therefore,optimising and gaining process knowledge about cell culture hasalso gained in interest. LÄS MER

  7. 20. Multivariate non-invasive measurements of skin disorders

    Författare :Josefina Nyström; Britta Lindholm-Sethson; Paul SLU Geladi; Lars Noergaard; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Multivariate Data Analysis; Non-invasive techniques; Clinical studies; Principal Component Analysis; Partial Least Squares Discriminant Analysis; Wilcoxon Signed Rank Sum Test; Near-InfraRed spectroscopy; Frequency Bio Impedance Analysis of whole body; Laser Doppler Imaging; Digital Colour Photography; Analytical chemistry; Analytisk kemi;

    Sammanfattning : The present thesis proposes new methods for obtaining objective and accurate diagnoses in modern healthcare. Non-invasive techniques have been used to examine or diagnose three different medical conditions, namely neuropathy among diabetics, radiotherapy induced erythema (skin redness) among breast cancer patients and diagnoses of cutaneous malignant melanoma. LÄS MER