Sökning: "Acute lymphatic leukaemia"

Hittade 4 avhandlingar innehållade orden Acute lymphatic leukaemia.

  1. 1. Practical application of machine learning for analyses of biological matrices and environmental phenomena

    Författare :Alexandra Walsh; Göteborgs universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Machine learning; Surface enhanced Raman spectroscopy; Acute lymphatic leukaemia; Volatile halogenated organic carbons; Marine algae; Doxorubicin; Principal component analysis; Multivariate statistics; Design of experiments; Waterlogged archaelogical wood; Transposed orthogonal partial least squares;

    Sammanfattning : This thesis presents research aimed at forwarding an understanding of machine learning methods as a method of studying complex matrices and environmental phenomena. A number of machine learning methods in the form of linear projection algorithms and statistical experimental designs were applied for qualitative analysis of different matrices. LÄS MER

  3. 2. Allogeneic stem cell transplantation in children : identification and prevention of complications : adoptive transfer of EBV-immunity

    Författare :Åsa Gustafsson Jernberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Children; CTL; EBV; Graft-versus-leukaemia; Stemcell transplantation; unrelated;

    Sammanfattning : Allogeneic stem cell transplantation (SCT) can cure leukaemia, aplastic anaemia, and some inborn errors of metabolism and immunodeficiencies in children. As only 113 of patients who need SCT have an HLA-identical sibling, the use of alternative donors has increased, to over 50% of all paediatric SCTs at our centre. LÄS MER

  4. 3. Prognostic and epidemiological factors in childhood leukemia : studies of p53 and MDM2 expression and of space-time clustering

    Författare :Britt Gustafsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Childhood leukaemia; MDM2; p53; immunohistochemistry; non-Hodgkin s lymphomas; space-time clustering; viral hypothesis;

    Sammanfattning : Although cure rates in acute childhood leukaemias have improved it remains a challenge to understand how molecular aberrations influence the prognosis of leukaemia and thus the choice of optimal therapy. Some studies have suggested that dysfunction of the tumour suppressor gene p53 or the oncogene MDM2 could indicate disease progression in children with leukaemia. LÄS MER

  5. 4. Hepatitis C virus infection : a nationwide study of associated morbidity and mortality

    Författare :Ann-Sofi Duberg; Erik Bäck; Karl Ekdahl; Rolf Hultcrantz; Anders Blaxhult; Johan Carlson; Örebro universitet; []
    Nyckelord :HCV; hepatitis C; epidemiology; non-Hodgkin s lymphoma; NHL; multiple myeloma; primary liver cancer; HCC; mortality; inpatient care; hospitalization; MEDICINE; MEDICIN; Infektionssjukdomar; Infectious Diseases; Epidemiology; Epidemiologi; Medicin; Medicine;

    Sammanfattning : The hepatitis C virus (HCV) was characterised in 1989. HCV was transmitted through transfusion of blood/blood products, but injection drug use is now the most common route of transmission. LÄS MER