Sökning: "oxidations"

Visar resultat 16 - 20 av 47 avhandlingar innehållade ordet oxidations.

  1. 16. Oxidation of Ketones: A (Chemo-) Enzymatic Approach Using Oxygenases and Hydrolases

    Författare :Georgina Chávez; Bioteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; cross linked enzyme aggregates.; caprolactone; perhydrolase; Lipase B from Candida antarctica;

    Sammanfattning : Oxidation reactions are important in organic chemistry as well as in nature. In industry, oxidations are commonly used for the synthesis of chemicals and pharmaceuticals, however such processes have a number of limitations, they use chlorinated solvents, stoichiometric oxidation reagents, and in some cases the reagents that have risks of explosion during transportation and storage. LÄS MER

  3. 17. Structural studies of R2 and R2–like proteins with a heterodinuclear Mn/Fe cofactor and enzymes involved in Mycobacterium tuberculosis lipid metabolism

    Författare :Charlotta Selina Andersson; Martin Högbom; Brian Fox; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; biokemi;

    Sammanfattning : Tuberculosis is a notorious disease responsible for the deaths of 1.4 million people worldwide. A third of the world's population is infected with Mycobacterium tuberculosis, the bacterium causing the disease. LÄS MER

  4. 18. Synthesis of lactosamine-containing carbohydrate structures and development for their easy assembly and conjugation

    Författare :Therese Buskas; Robert Madsen; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic Chemistry; organisk kemi;

    Sammanfattning : This thesis is based on four publications. The first chapter describes preparation of anomerically pure thioethyl-, thiophenyl-, and n-pentenyl 2-azido-2-deoxy glycosyl building blocks from easily accessible per-acetylated glycosamines. LÄS MER

  5. 19. Hydrolytic and oxidative catalytic activities of bio-inspired dinuclear metal complexes

    Författare :Biswanath Das; Kemisk fysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bioinorganic Chemistry; Metalloenzymes; Catalyst; Transition states; Phosphoesterase;

    Sammanfattning : A number of homo- and heterodinuclear complexes have been synthesized as structural and functional models for the the active sites of phosphoesterases and soluble methane monooxygenases. The complexes are based on four new dinucleating ligands containing a central, potentially bridging, phenolate moiety. LÄS MER

  7. 20. Electrochemical and Enzymatic In Vitro Studies on Reactive Drug Metabolites. Synthesis, Characterization and Avoidance

    Författare :Tove Johansson Mali´n; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cytochrome P450; Drug; Electrochemical oxidation; Electrochemistry; Intermediate; Metabolism; Metabolic activation; Mimicry; Reactive Metabolite; Trapping.;

    Sammanfattning : During development of pharmaceuticals, it is essential to as early as possible identify and preferably avoid formation of reactive metabolites and intermediates. Reactive metabolites may represent obstacles in the development and use of drugs, due to their potential toxicity. LÄS MER