Sökning: "monooxygenase"

Visar resultat 1 - 5 av 17 avhandlingar innehållade ordet monooxygenase.

  1. 1. High (valent) on O2 : Ribonucleotide Reductase and Methane Monooxygenase

    Författare :Juliane John; Martin Högbom; Pål Stenmark; Peter Moody; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ribonucleotide Reductase; Methane Monooxygenase; biokemi; Biochemistry;

    Sammanfattning : Macromolecular X-ray crystallography (MX) is a powerful method to investigate protein structures. However, proteins with redox-active centres and radicals are very susceptible to photoreduction. LÄS MER

  3. 2. Bacterial cytochromes P450-Studies on Cytochrome P450 102A2 and P450 102A3 of Bacillus subtilis

    Författare :Mattias Gustafsson; Avdelningen för medicinsk mikrobiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Microbiology; AbrB; Spo0A; monooxygenase; heme; Bacillus subtilis; Cytochrome P450; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Cytochromes P450 constitute a super-family of heme containing mixed function mono-oxygenases that is found in all branches of life. They introduce single oxygen atoms, mostly in the form of hydroxyl groups, into lipophilic substances and thereby render them more hydrophilic and susceptible to further reactions. LÄS MER

  4. 3. To metal, or not to metal : Diverse mechanisms of O2-activation and radical storage in the ferritin superfamily

    Författare :Vivek Srinivas; Martin Högbom; Brian Hoffman; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Metalloprotein; di-metal; Oxygen activation; Substrate oxidation; Ribonucleotide reductase; Radical; DOPA; ADE-DOT; X-Ray free-electron laser; soluble Methane monooxygenase; Biochemistry; biokemi;

    Sammanfattning : Proteins in the Ferritin-like superfamily are characterized by a four alpha-helical structural motif. These proteins are distributed across all three kingdoms of life and perform a wide range of functions. LÄS MER

  5. 4. Structural and functional investigation of underexplored carbohydrate-active enzyme families

    Författare :Andrea Seveso; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; carbohydrate-active enzymes; lytic polysaccharide monooxygenase; plant biomass degradation; copper radical oxidases; carbohydrate esterase; protein structure determination; protein structure prediction;

    Sammanfattning : The known consequences of the current fossil-based economy require a transition towards a bio-based economy. Development of biorefineries in which plant biomass can be utilized as a renewable source of energy and building blocks to produce both commodities and high-value products, is a key step in this transition. LÄS MER

  7. 5. Xenobiotic-metabolizing enzymes and enzymes involved in the metabolism of reactive oxygen species in the porcine ovary : subcellular distributions and levels of expression during follicular maturation and in the non-pregnant and pregnant corpus luteum

    Författare :Maria Eliasson; Thomas Friedberg; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Sammanfattning : The polycyclic aromatic hydrocarbon (PAH) 7,12-dimethylbenz(a)anthracene (DMBA) is metabolized by both porcine ovarian microsomes and mitochondria, with the highest activity being seen in the corpus luteum. Microsomal DMBA monooxygenase activity is inhibited by inhibitors of the CYP450 system and by 17-bestradiol, thus indicating involvement of CYP1B1. LÄS MER