Sökning: "protein structure prediction"

Visar resultat 1 - 5 av 78 avhandlingar innehållade orden protein structure prediction.

  1. 1. Protein structure prediction Zinc-binding sites, one-dimensional structure and remote homology

    Detta är en avhandling från Stockholm : Department of Materials and Environmental Chemistry (MMK), Stockholm University

    Författare :Nanjiang Shu; Stockholms universitet.; [2010]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; protein structure prediction; zinc-binding; profile; homology detection; shape string; NATURAL SCIENCES Biology Other biology Bioinformatics; NATURVETENSKAP Biologi Övrig biologi Bioinformatik; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi; NATURAL SCIENCES Chemistry Biochemistry; NATURVETENSKAP Kemi Biokemi; Structural Chemistry; strukturkemi;

    Sammanfattning : Predicting the three-dimensional (3D) structure of proteins is a central problem in biology. These computationally predicted 3D protein structures have been successfully applied in many fields of biomedicine, e.g. family assignments and drug discovery. LÄS MER

  2. 2. Protein Structure Prediction Model Building and Quality Assessment

    Detta är en avhandling från Stockholm : Institutionen för biokemi och biofysik

    Författare :Björn Wallner; Stockholms universitet.; [2005]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein structure prediction; proteinstrukturförutsägelse; NATURAL SCIENCES Biology Other biology Bioinformatics; NATURVETENSKAP Biologi Övrig biologi Bioinformatik;

    Sammanfattning : Proteins play a crucial roll in all biological processes. The wide range of protein functions is made possible through the many different conformations that the protein chain can adopt. The structure of a protein is extremely important for its function, but to determine the structure of protein experimentally is both difficult and time consuming. LÄS MER

  3. 3. Ensemble methods for protein structure prediction

    Detta är en avhandling från Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Författare :Marcin J. Skwark; Stockholms universitet.; [2013]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein structure prediction; model quality assessment; contact prediction; homology modeling; ab-initio prediction; consensus prediction; structural bioinformatics; bioinformatics; protein structure; biokemi; inriktning teoretisk kemi; Biochemistry with Emphasis on Theoretical Chemistry;

    Sammanfattning : Proteins play an essential role in virtually all of life's processes. Their function is tightly coupled to the three-dimensional structure they adopt.Solving protein structures experimentally is a complicated, time- and resource-consuming endeavor. LÄS MER

  4. 4. From Sequence to Structure Using predicted residue contacts to facilitate template-free protein structure prediction

    Detta är en avhandling från Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Författare :Mirco Michel; Stockholms universitet.; [2017]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein bioinformatics; protein structure prediction; contact prediction; machine learning; biokemi med inriktning mot bioinformatik; Biochemistry towards Bioinformatics;

    Sammanfattning : Despite the fundamental role of experimental protein structure determination, computational methods are of essential importance to bridge the ever growing gap between available protein sequence and structure data. Common structure prediction methods rely on experimental data, which is not available for about half of the known protein families. LÄS MER

  5. 5. On protein structure, function and modularity from an evolutionary perspective

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Robert Pilstål; Linköpings universitet.; Linköpings universitet.; [2018]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bioinformatics; structure; biology; intrinsical; disorder; protein; sequence; evolution; mutation; epistasis; function; allostery; dynamics; simulation; prediction; graph; network; bioinformatik; struktur; biologi; strukturbiologi; intrinsiellt; oordnad; protein; sekvens; evolution; mutation; epistasis; funktion; allosteri; dynamik; simulation; prediktion; graf; nätverk;

    Sammanfattning : We are compounded entities, given life by a complex molecular machinery. When studying these molecules we have to make sense of a diverse set of dynamical nanostructures with wast and intricate patterns of interactions. LÄS MER