Sökning: "mass"

Visar resultat 6 - 10 av 4957 avhandlingar innehållade ordet mass.

1. 6. Improved Neuropeptide Identification : Bioinformatics and Mass Spectrometry

   Författare :Maria Fälth Savitski; Per Andrén; David Fenyö; Per Svenningsson; Ronald Beavis; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bioinformatics; neuropepides; database; peptide identification; peptide fragmentation; mass spectrometry; tandem mass spectromerty; Bioinformatics; Bioinformatik;

   Sammanfattning : Bioinformatic methods were developed for improved identification of endogenous peptides using mass spectrometry. As a framework for these methods, a database for endogenous peptides, SwePep, was created. It was designed for storing information about endogenous peptides including tandem mass spectra. LÄS MER

3. 7. Novel strategies to increase throughput and differentiate lipid isomers in mass spectrometry imaging : Development of computational tools and complex mass spectrometric methods for nanospray desorption electrospray ionization

   Författare :Johan Lillja; Ingela Lanekoff; Daniel Globisch; Orešič Matej; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mass spectrometry; Mass spectrometry imaging; Tandem mass spectrometry; Silver cationization; Mathematical modeling; Lipid; Lipid isomer; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

   Sammanfattning : In this thesis, method development for improved analyte identification and throughput in mass spectrometry imaging (MSI) is discussed. In MSI, the spatial distribution of analytes from a sample is determined and visualized, information about the detected molecules interaction within the sample can thereby the deduced. LÄS MER

4. 8. Weigh them all! : Cosmological searches for the neutrino mass scale and mass ordering

   Författare :Sunny Vagnozzi; Katherine Freese; Lars Bergström; Alessandra Silvestri; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; neutrinos; neutrino mass; neutrino mass ordering; cosmology; cosmic microwave background; large-scale structure; galaxy surveys; dark energy; cosmic inflation; data analysis; teoretisk fysik; Theoretical Physics;

   Sammanfattning : The elusive neutrinos are among the most intriguing constituents of the particle zoo. The observation of neutrino flavour oscillations, indicating that neutrinos are massive, provides the only direct evidence for physics beyond the Standard Model. LÄS MER

5. 9. Exploring Pharmaceutical Mass Customization

   Författare :Maria Daniela Irene Siiskonen; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; mass customization; pharmaceutical product customization; postponement; product modularization; process flexibility;

   Sammanfattning : The core purpose of therapeutic pharmaceutical products is to induce responses to various diseases in patients and thereby bring societal value; however, unmet medical needs currently prevail. Conventional treatment of these products predominantly embraces a one-size-fits-all design and is manufactured in a mass-production context. LÄS MER

7. 10. Mass Spectrometry-based Neuroproteomics : Deciphering the Human Brain Proteome

   Författare :Sravani Musunuri; Jonas Bergquist; Ganna Shevchenko; Jean-Charles Sanchez; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Brain; Proteomics; Mass spectrometry; Alzheimer s disease; Traumatic brain injury; Membrane proteins; Sample preparation; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

   Sammanfattning : Mammalian brain is challenging to study due to its heterogeneity and complexity. However, recent advances in molecular imaging, genomics and proteomics have contributed significantly to achieve insights into molecular basis of brain function and pathogenesis of neurological disorders. LÄS MER