Sökning: "Lipid"

Visar resultat 1 - 5 av 1489 avhandlingar innehållade ordet Lipid.

1. 1. α-synuclein interactions with lipid membranes

   Författare :Katarzyna Makasewicz; NanoLund: Centre for Nanoscience; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; alpha-Synuclein; lipid membranes; protein-lipid interactions; binding cooperativity; membrane remodeling; protei-lipid co-aggregation;

   Sammanfattning : α-synuclein is an intrinsically disordered protein implicated in synaptic vesicle trafficking at the synapse. Accumulation of α-synuclein in the form of amyloid deposits coincides with the loss of dopaminergic neurons in Parkinsons disease. LÄS MER

3. 2. Novel strategies to increase throughput and differentiate lipid isomers in mass spectrometry imaging : Development of computational tools and complex mass spectrometric methods for nanospray desorption electrospray ionization

   Författare :Johan Lillja; Ingela Lanekoff; Daniel Globisch; Orešič Matej; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mass spectrometry; Mass spectrometry imaging; Tandem mass spectrometry; Silver cationization; Mathematical modeling; Lipid; Lipid isomer; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

   Sammanfattning : In this thesis, method development for improved analyte identification and throughput in mass spectrometry imaging (MSI) is discussed. In MSI, the spatial distribution of analytes from a sample is determined and visualized, information about the detected molecules interaction within the sample can thereby the deduced. LÄS MER

4. 3. Membrane-Polymer Interactions in Lipid Vesicles

   Författare :Ilona Wegrzyn; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; lipid nanotube; liposome; multifunctional pipette; PNIPAAm; lipid bilayer; giant unilamellar vesicle;

   Sammanfattning : Membrane related biological processes are commonly investigated in artificial biomimetic experimental systems. One of the most versatile models is based upon giant unilamellar phospholipid vesicles (liposomes), which are artificially generated spherical lipid structures in an aqueous environment. LÄS MER

5. 4. Lipid peroxidation in vivo : Evaluation and application of methods for measurement

   Författare :Eva Södergren; Uppsala universitet; []
   Nyckelord :Medical sciences; lipid peroxidation; hydroperoxides; F2-isoprostanes; MDA; prostaglandins; measurement; carbon tetrachloride; vitamin E; dietary fat quality; rapeseed oil; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Geriatrics; geriatrik;

   Sammanfattning : Lipid peroxidation is thought to be an important factor in the pathophysiology of a number of diseases and in the process of ageing, but its measurement in vivo has been difficult. The aim of this thesis was to evaluate methods for measurement of lipid peroxidation in vivo that are suitable for clinical investigations, and to apply these methods in animal and human studies investigating basal conditions and situations associated with increased lipid peroxidation. LÄS MER

7. 5. Mesoporous supported lipid bilayers

   Författare :Maria Claesson; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; FRAP; Lipid bilayer; Mesoporous; AFM; Vesicle; Titania; Silica; QCM-D;

   Sammanfattning : AbstractLipid bilayers are commonly used as simplified model systems of living cell membranes. They have shown to be important components in the development of biosensing devices where the bilayer acts as a host for transmembrane proteins, such as ion channels, that are utilized as sensing elements. LÄS MER