Sökning: "lncRNA"

Visar resultat 6 - 10 av 22 avhandlingar innehållade ordet lncRNA.

  1. 6. Structure studies of membrane associated proteins by transmission electron microscopy

    Författare :Zuoneng Wang; Carsten Mim; Anna Sundborger Lunna; KTH; []
    Nyckelord :peripheral membrane protein PMP ; BAR protein; membrane curvature; actin dynamic; transmission electron microscopy; liposomes; Technology and Health; Teknik och hälsa;

    Sammanfattning : Cell membranes need to change their shapes during many cellular processeslike protein trafficking, cytokinesis and membrane homeostasis. The lattershuttles lipids, synthesized in the endoplasmic reticulum, to all membranouscompartments. LÄS MER

  3. 7. Immune modulation in serous epithelial ovarian cancer : focus on the role of tumor-derived exosomes

    Författare :Alireza Labani Motlagh; Lucia Mincheva-Nilsson; Ola Winqvist; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ovarian cancer; EOC; HGSC; exosomes; NKG2D; MICA B; ULBP; DNAM-1; PVR; nectin-2; lncRNAs; immune suppression; anti-tumor immunity; NK-cell cytotoxicity; cytokines; Th1; Th2; T regulatory response; inflammation; tumor microenvironment;

    Sammanfattning : Serous epithelial ovarian cancer (EOC) is a potent suppressor of the immune defense. Here, we studied interactions between EOC and the immune system that lead to escape from tumor immune surveillance. LÄS MER

  4. 8. Understanding the role of non-coding RNAs in skin homeostasis and cancer

    Författare :Kunal Das Mahapatra; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The epidermis is a stratified epithelium with continuous self-renewing capacity. As the outermost layer of our body, it provides a protective barrier against external trauma, produces pigmentation, and keeps the skin hydrated. Keratinocytes are the primary constituent cells type within the epidermis. LÄS MER

  5. 9. Non-coding RNAs and Extracellular Vesicles in Cutaneous Squamous Cell Carcinoma

    Författare :Chen Li; Andor Pivarcsi; Gareth Inman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cutaneous squamous cell carcinoma; microRNA; long non-coding RNA; extracellular vesicle;

    Sammanfattning : Cutaneous squamous cell carcinoma (cSCC) ranks among the most widespread malignancies with metastatic potential. Investigating the molecular mechanism of tumorigenesis will enhance our understanding of cSCC. Aberrant expression of non-coding RNAs has been extensively reported in human cancers. LÄS MER

  7. 10. Non-coding RNA-based therapeutics and biomarkers for treatment and detection of vascular disease

    Författare :Greg Winski; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cardiovascular disease (CVD), with atherosclerosis as its main underlying pathology, is the most prominent cause of death worldwide. Progression and rupture of atherosclerotic plaques lead to potential adverse pathological events such as myocardial infarction and stroke. LÄS MER