Sökning: "large-scale discovery"

Visar resultat 1 - 5 av 59 avhandlingar innehållade orden large-scale discovery.

1. 1. Statistical and machine learning methods to analyze large-scale mass spectrometry data

   Författare :Matthew The; Lukas Käll; Oliver Kohlbacher; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mass spectrometry - LC-MS MS; statistical analysis; data processing and analysis; protein inference; large-scale studies; simulation; protein quantification; clustering; machine learning; Bayesian statistics; Bioteknologi; Biotechnology;

   Sammanfattning : Modern biology is faced with vast amounts of data that contain valuable information yet to be extracted. Proteomics, the study of proteins, has repositories with thousands of mass spectrometry experiments. These data gold mines could further our knowledge of proteins as the main actors in cell processes and signaling. LÄS MER

3. 2. Statistical and machine learning methods to analyze large-scale mass spectrometry data

   Författare :Matthew The; Lukas Käll; Fredrik Levander; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mass spectrometry - LC-MS MS; statistical analysis; data processing and analysis; protein inference; large-scale studies; simulation; Bioteknologi; Biotechnology;

   Sammanfattning : As in many other fields, biology is faced with enormous amounts ofdata that contains valuable information that is yet to be extracted. The field of proteomics, the study of proteins, has the luxury of having large repositories containing data from tandem mass-spectrometry experiments, readily accessible for everyone who is interested. LÄS MER

4. 3. Self-Management for Large-Scale Distributed Systems

   Författare :Ahmad Al-Shishtawy; Vlassov Vlassov; Seif Haridi; Per Brand; Leandro Navarro Moldes; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Self-Management; Autonomic Computing; Control Theory; Distributed Systems; Grid Computing; Cloud Computing; Elastic Services; Key-Value Stores; SRA - ICT; SRA - Informations- och kommunikationsteknik;

   Sammanfattning : Autonomic computing aims at making computing systems self-managing by using autonomic managers in order to reduce obstacles caused by management complexity. This thesis presents results of research on self-management for large-scale distributed systems. LÄS MER

5. 4. Distributed Peer Discovery in Large-Scale P2P Streaming Systems : Addressing Practical Problems of P2P Deployments on the Open Internet

   Författare :Raul Jimenez; Seif Haridi; Björn Knutsson; Arnaud Legout; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

   Sammanfattning : Peer-to-peer (P2P) techniques allow users with limited resources to distribute content to a potentially large audience by turning passive clients into peers. Peers can self-organize to distribute content to each other, increasing the scalability of the system and decreasing the publisher’s costs, compared to a publisher distributing the data himself using a content delivery network (CDN) or his own servers. LÄS MER

7. 5. Evolution and viral mimicry of short linear motif-mediated interactions

   Författare :Filip Mihalič; Per Jemth; Leo James; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; phage display; protein-protein interactions; large-scale discovery; short linear motifs; viral mimcry; viral hijacking; Biokemi; Biochemistry; Medical Biochemistry; Medicinsk biokemi;

   Sammanfattning : Proteins are one of the most fundamental building blocks of life and their interactions regulate every cellular process. Historically they have been conceptualized as predominantly folded entities with well-defined secondary and tertiary structures. LÄS MER