Sökning: "klaesson"

Visar resultat 1 - 5 av 15 avhandlingar innehållade ordet klaesson.

  1. 1. Development of DNA-based methods for analysis of protein interactions

    Författare :Axel Klaesson; Ola Söderberg; Mats Nilsson; Cristina Al-Khalili Szigyarto; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; In situ proximity ligation assay PLA ; rolling circle amplification RCA ; Hybridization chain reaction HCR ; proxHCR; Oligonucleotide design; Protein-protein interactions; Post-translational modifications.; Farmaceutisk vetenskap; Pharmaceutical Science; Molekylär cellbiologi; Molecular Cellbiology;

    Sammanfattning : In situ proximity ligation assay (PLA) is a method for detection of protein interactions, post-translational modifications (PTMs) and individual proteins that allows information about their localization in a cell or tissue to be extracted. The method is based on oligonucleotide-conjugated antibodies (proximity probes) that upon binding of two epitopes in close proximity give rise to an amplifiable DNA circle. LÄS MER

  3. 2. A Study of Localisation Economies and the Transport Sector

    Författare :Johan Klaesson; Jönköping University; []
    Nyckelord :;

    Sammanfattning : This thesis consists of five individual essays, and a common introduction, sharing the general idea that the location of economic activities matters. Four of the essays explicitly introduce a transport sector that has impacts on the location and economic efficiency of other activities. LÄS MER

  4. 3. Immune moldulatory effects of intravenous immunoglobulin in vitro and after allogeneic bone marrow transplantation

    Författare :Sven Klaesson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :IVIG; IgG; F ab 2; Fc; immune modulation; T cell responses; Bcell responses; cytokines; bone marrow transplantation; infections; CMV; graft-versus-hostdisease;

    Sammanfattning : Intravenous immunoglobulin (IVIG) has been used in patients with immunodeficiencies and various autoimmune diseases. Its immune modulatory effect is well documented. In allogeneic bone marrow transplantation (BMT) IVIG has been used to reduce the incidence of infections and graft-versus-host-disease (GVHD). LÄS MER

  5. 4. Nonmarket Interactions and Density Externalities

    Författare :Johan P. Larsson; Johan Klaesson; Martin Andersson; Henri de Groot; Jönköping University; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES;

    Sammanfattning : The four individual papers in this thesis all explore some aspect of the relationship between productivity and the density of economic activity.The first paper (co-authored with Martin Andersson, and Johan Klaesson) establishes the general relationship between regional density and average labor productivity; a relationship that is particularly strong for workers in interactive professions. LÄS MER

  7. 5. Transport accessibility, wholesale trade and spatial development

    Författare :Therese Norman-Monroe; Johan Klaesson; Charlie Karlsson; Janet E. Kohlhase; Jönköping University; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES;

    Sammanfattning : This thesis comprises four independent papers, which all explore some aspect of the relationship between accessibility and spatial development. The central question I pose is how improved accessibility to transportation services, human capital, jobs, or the market contributes to the spatial variation in economic development. LÄS MER