Sökning: "intracellular invasion"

Visar resultat 16 - 20 av 50 avhandlingar innehållade orden intracellular invasion.

  1. 16. IGF-1R : studies on the expression and role in transformation

    Författare :Natalia Natalishvili; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Transformation is a complex nonlinear multistep process during which normal cell becomes cancerous. Main characteristics of transformed cells include uncontrolled growth, invasion and metastasis. LÄS MER

  3. 17. Non-canonical TGFb signaling pathways in prostate cancer

    Författare :Jie Song; Marene Landström; Staffan Strömblad; Umeå universitet; []
    Nyckelord :TGFβ; TβRI; TRAF6; ubiquitination; APPL1; p85; AKT; PKCζ;

    Sammanfattning : Prostate cancer is the second leading cause of cancer-related death in men in the Western world. Deregulation of transforming growth factor β (TGFβ) signaling pathway is frequently detected in prostate cancer and contributes to tumor growth, migration, and invasion. LÄS MER

  4. 18. Microbe-induced apoptosis in phagocytic cells and its role in innate immunity

    Författare :Robert Blomgran; Olle Stendahl; Limin Zheng; Boris Zhivotovsky; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; apoptosis; cell death; inflammation; innate immunity; microbiology; neutrophil; macrophage; phagocyte; Medical microbiology; Medicinsk mikrobiologi;

    Sammanfattning : Apoptosis, or programmed cell death, is a controlled process by which aged or damages cells are eliminated in multicellular organisms. Neutrophils, short-lived phagocytes of the innate immune system, are highly equipped effectors that can sense, locate, ingest and kill bacterial pathogens. LÄS MER

  5. 19. Oxidoreductases and RNA degradosome controlling virulence-associated traits of Salmonella enterica serovar Typhimurium

    Författare :Naeem Anwar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The oxidative stress response is a fundamental and primitive mode of innate immune defense in nearly all forms of life. The host oxidative stress response becomes truly important and effective especially against intracellular pathogens such as Salmonella. Pathogens have evolved diverse mechanisms to withstand the oxidative responses. LÄS MER

  7. 20. Studies on the roles of stromal CXCL14 in tumor growth, progression and metastasis formation

    Författare :Elin Sjöberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cancer consists of several diseases that are characterized by accumulation of genetic and epigenetic alterations that provide cells with certain capabilities to form tumors. Among these acquired capabilities are enhanced invasion that allow cancer cells to escape from the primary tumor, enter the circulation and eventually reach distant tissues where they form metastasis. LÄS MER