Sökning: "intracellular invasion"

Visar resultat 21 - 25 av 50 avhandlingar innehållade orden intracellular invasion.

  1. 21. Chemical genetics and immunomodulation in Salmonella enterica serovar typhimurium infection

    Författare :Speranta Banesaru; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Salmonella sp. are versatile bacteria that survive and replicate in a plethora of environmental niches and hosts, including humans. The illnesses caused by various serovars in humans range from mild gastroenteritis to severe systemic disease such as typhoid fever that still cause an important number of casualties especially in developing countries. LÄS MER

  3. 22. PKB/Akt kinase localization and role in stemness maintenance in cancer

    Författare :Mayur Vilas Jain; Karin Roberg; Piotr Religa; Mehrdad Rafat; Mahvash Tavassoli; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Cancer incidence rates have increased over the last decade. Currently available therapies are only moderately effective in targeting cancer cells. Established cancer treatment protocols fail to eliminate populations of cancer stem cells (CSCs), which develop resistance against the chemotherapeutic drugs and lead to cancer recurrence. LÄS MER

  4. 23. Immune evasion and dissemination of Toxoplasma gondii

    Författare :Henrik Lambert; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Toxoplasma gondii is an obligate intracellular protozoan parasite which propagates in a complex life cycle where infection of Felidae family-members (Cats) results in sexual recombination whereas all other warm-blooded animals are intermediate hosts. Approximately one third of the human population is estimated to be chronically infected by this parasite. LÄS MER

  5. 24. Conditions associated with increased growth hormone and prolactin sensitivity

    Författare :Amira Said Mohammed Alkharusi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Growth Hormone (GH) and Prolactin (PRL) are critical regulators of body growth and metabolism. Secretion and actions of GH and PRL are regulated at several levels and by different factors. The biological actions of these hormones are initiated by their binding to the respective membrane bound receptors of GH and PRL (GHR and PRLR). LÄS MER

  7. 25. Deciphering microglia plasticity in glioma

    Författare :Dalel Saidi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Microglia are the innate immune cells of the brain. One of the main characteristics of microglia is its extremely plasticity, which is necessary for them to deal with changing circumstances. Activation of microglia can contribute to contrasting effects by either proinflammatory, anti-inflammatory, or tumor-supportive phenotypes. LÄS MER