Sökning: "heme oxygenase"
Visar resultat 11 - 14 av 14 avhandlingar innehållade orden heme oxygenase.
11. Renal Ischemia/Reperfusion Injury in Diabetes : Experimental Studies in the Rat
Sammanfattning : Diabetes mellitus (DM) is one of the leading causes of end stage renal failure. An increased susceptibility to renal ischemia/reperfusion (I/R)-injury was found in DM rats. Unilateral renal ischemia for as short as 20 minutes led to an irreversible progressive injury in DM kidneys, whereas the injury in non-DM kidneys was almost reversible. LÄS MER
12. Pathophysiology of blood-brain barrier, brain edema and cell injury following hyperthermia : New role of heat shock protein, nitric oxide and carbon monoxide : an experimental study in rat using light and electron microscopy
Sammanfattning : This thesis deals with the molecular mechanisms of hyperthermia induced brain damage in rats. The results clearly establish that hyperthermia caused by 4 h heat stress at 38° C is associated with a breakdown of the blood-brain barrier (BBB) permeability which seems to be instrumental in causing brain edema and cell injury. LÄS MER
13. PACAP and airway regulation with special reference to smooth muscle and neutrophils
Sammanfattning : The investigations focus on the neuropeptidepituitary adenylate cyclase-activating peptide and its effects on airway regulation, with emphasis on smooth muscle relaxation and neutrophil activation and migration. In the nasal mucosa, PACAP-containing nerve fibers were localized invascular smooth muscle and close to seromucous glands. LÄS MER
14. Genetic and epigenetic studies of acute myeloid leukemia and therapeutic possibilities
Sammanfattning : Acute myeloid leukaemia (AML) is malignant tumour that forms in the bone marrow and arises from immature myeloid progenitors. Consequently, this leads to excessive accumulation of dysfunctional blast cells and lack of normal blood cells. LÄS MER