Sökning: "genome reduction"

Visar resultat 21 - 25 av 83 avhandlingar innehållade orden genome reduction.

  1. 21. Bacterial adaption to novel selection pressures

    Författare :Annika Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Evolution; bacterial adaptation; mutation rate; population size; mutation accumulation; fitness; antibiotic resistance; compensation; genetic drift; genome reduction;

    Sammanfattning : The rates and trajectories of bacterial evolution are determined both by microbial factors and environmental parameters. In this thesis 1 have investigated how bacterial mutation rates and selection pressure affect the rate and extent of adaptation to novel environments. LÄS MER

  3. 22. Advancing Metabolic Engineering through Combination of Systems Biology and Adaptive Evolution

    Författare :Kuk-ki Hong; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; metabolic engineering; galactose utilization; systems biology; Ras PKA signaling pathway; evolutionary engineering; pleiotropy of evolutionary strategies;

    Sammanfattning : Understanding evolutionary strategies of microorganisms may provide opportunities foradvanced strain development with the aim to produce valuable bio-products from renewablebiomass resources. Through evolutionary processes, microorganisms can attain new traitsassociated with genetic changes that may be useful for the construction of improved strains. LÄS MER

  4. 23. Culture-independent methods and high-throughput sequencing applied to evolutionary microbial genomics

    Författare :Anders E. Lind; Thijs JG Ettema; Purificación López-García; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Single cell genomics; metagenomics; amplicon; archaea; haloarchaea; endosymbiosis; ciliate; hydrogenosome; tree reconciliation;

    Sammanfattning : Culture-independent methods allow us to better understand the diversity of microorganisms on earth. By omitting the culturing step, we can gain access to species previously out of our reach.To better capture and understand the diversity of microorganisms, we have developed an alternative to 16S amplicon sequencing. LÄS MER

  5. 24. Understanding the role and regulation of Polη for damage-induced cohesion

    Författare :Pei-Shang Wu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In response to DSBs, de novo sister chromatid cohesion can be established after DNA replication in Saccharomyces cerevisiae. The damage-induced cohesion is formed close to the break and genome-wide on undamaged chromosomes. LÄS MER

  7. 25. Studies towards late blight control in potato

    Författare :Laith Moushib; Molekylär cellbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Oomycetes; plant induced resistance; sustainable agriculture; plant defence activators; plant innate immunity; potato; late blight;

    Sammanfattning : Abstract The oomycete Phytophthora infestans, which causes the devastating late blight disease of potato, is notorious for developing resistance to conventional control strategies (fungicide application and resistance breeding by introgression of R gene). To increase our tool box of disease management strategies available to combat P. LÄS MER